Navegando por Palavras-chave "índice proliferativo"

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    Associação entre tamanho e potencial proliferativo em neurinomas do acústico
    (Academia Brasileira de Neurologia - ABNEURO, 2006-03-01) Tella, Oswaldo Inácio de [UNIFESP]; Stávale, João Norberto [UNIFESP]; Herculano, Marco Antonio [UNIFESP]; Paiva Neto, Manoel Antonio de [UNIFESP]; Onishi, Franz Jooji [UNIFESP]; Guimarães Filho, Francisco de Assis Vaz [UNIFESP]; Silva, Luciano Ricardo França e [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Hospital Professor Edmundo Vasconcelos; Faculdade de Medicina de Jundiaí
    Acoustic neuromas are the most common tumors in the cerebellopontine angle. The molecular mechanisms involved in generation and growth of these tumors are not completly elucidated. Many radiological, clinic and imunohistochemystry data were correlated to tumor growth. We studied 11 acoustic neuromas surgically treated at Hospital São Paulo/UNIFESP and correlated clinical and radiological data with proliferative index (Ki-67). The size of the tumors were positively correlationated with proliferative index. No other correlation had statistic significativity.
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    Meningeoma de goteira olfatória: relação entre achados clínico-radiológicos e índice proliferativo (Mib-1)
    (Academia Brasileira de Neurologia - ABNEURO, 2006-03-01) Paiva Neto, Manoel Antonio de [UNIFESP]; Tella Jr, Oswaldo Inácio de [UNIFESP]; Herculano, Marco Antonio [UNIFESP]; Stávale, João Norberto [UNIFESP]; Bonatteli, Antonio Pádua Furquim [UNIFESP]; Hospital Edmundo Vasconcelos; Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE: The aim of this study is to correlationate demografic, radiologic features and proliferative index defined by imunohistochemical expression of Mib-1 in olfactory groove meningiomas, and to observe possible predictive factors of recurrence of this tumor. METHOD: There were analysed demografic, clinical and radiological features of 15 patients with olfactory groove meningioma. Fifteen paraffin-embebed tumors were studied by imunohistochemical methods for the expression of proliferative index by the Mib-1. RESULTS: There was a statiscally positive correlation between tumoral and edema volumes. There was no correlation betweem Mib-1, tumoral volume, tumoral edema and frontal skull base abnormalities. Two cases with tumor recurrence had proliferative indices higher than the mean index. CONCLUSION: Larger tumors were more susceptible to develop peritumoral edema. The proliferative índex has no positive correlation with tumoral volume, edema volumes and skull base invasion, but probably it is associated with tumoral recurrence.