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- ItemSomente MetadadadosDescriptive analysis of the masticatory and salivary functions and gustatory sensitivity in healthy children(Hindawi Publishing Corp, 2016) Salome Marquezin, Maria Carolina; Pedroni-Pereira, Aline; Araujo, Darlle Santos; Rosar, Joao Vicente; Barbosa, Tais S.; Castelo, Paula Midori [UNIFESP]Objective: The objective of this study is to better understand salivary and masticatory characteristics, this study evaluated the relationship among salivary parameters, bite force (BF), masticatory performance (MP) and gustatory sensitivity in healthy children. The secondary outcome was to evaluate possible gender differences.Materials and methods: One hundred and sixteen eutrophic subjects aged 7-11 years old were evaluated, caries-free and with no definite need of orthodontic treatment. Salivary flow rate and pH, total protein (TP), alpha-amylase (AMY), calcium (CA) and phosphate (PHO) concentrations were determined in stimulated (SS) and unstimulated saliva (US). BF and MP were evaluated using digital gnathodynamometer and fractional sieving method, respectively. Gustatory sensitivity was determined by detecting the four primary tastes (sweet, salty, sour and bitter) in three different concentrations. Data were evaluated using descriptive statistics, Mann-Whitney/t-test, Spearman correlation and multiple regression analysis, considering =0.05.Results: Significant positive correlation between taste and age was observed. CA and PHO concentrations correlated negatively with salivary flow and pH
- ItemAcesso aberto (Open Access)Pharmacological treatment for kleine-levin syndrome(Wiley-blackwell, 2016) de Oliveira, Marcio M. [UNIFESP]; Conti, Cristiane [UNIFESP]; Prado, Gilmar F. [UNIFESP]Background This is an updated version of the original Cochrane review, published in 2009, Issue 2. Kleine-Levin syndrome (KLS) is a rare disorder that mainly affects adolescent men. It is characterised by recurrent episodes of hypersomnia, usually accompanied by hyperphagia, cognitive and mood disturbances, abnormal behaviour, such as hypersexuality, and signs of dysautonomia. In 1990, the diagnostic criteria for Kleine-Levin syndrome were modified in the International Classification of Sleep Disorders, where KLS was defined as a syndrome comprised of recurring episodes of undue sleepiness lasting some days, which may or may not be associated with hyperphagia and abnormal behaviour. According to the International Classification of Sleepiness Disorders, 3rd version (ICSD-3), revised in 2014, the Kleine-Levin syndrome is a disorder characterized by recurrent episodes of hypersomnia that last from two days to four weeks, with at least annual recurrence, and hyperphagia (rapid consumption of a large amount of food), usually with onset in early adolescence in males but occasionally in later life and in women. A monosymptomatic form of the disorder with hypersomnia only can occur without binge eating or hypersexuality. The cause of Kleine-Levin syndrome remains unknown, and several treatment strategies have been used. Some medications have been reported to provide benefit in the treatment of patients with KLS, but because of the rarity of the condition, no long-term follow-up therapies have yet been described. Objectives This review aimed to evaluate: 1. whether pharmacological treatment for Kleine Levin syndrome was effective and safe. 2. which drug or category of drugs was effective and safe. Search methods For the latest update, we searched the following sources: the Cochrane Epilepsy Group Specialized Register (7 April 2016)
- ItemSomente MetadadadosPhotoelectrocatalytic oxidation of methyl orange on a tio2 nanotubular anode using a flow cell(Wiley-v c h verlag gmbh, 2016) Jose Martin de Vidales, Maria; Mais, Laura; Saez, Cristina; Canizares, Pablo; Walsh, Frank C.; Rodrigo, Manuel A.; Rodrigues, Christiane de Arruda [UNIFESP]; de Leon, Carlos PonceMethyl orange from water was removed by photocatalytic anodic oxidation using a titanium dioxide array surface. The coating was prepared by anodizing a titanium plate in an ethylene glycol electrolyte-containing NH4F followed by heat treatment to realize a photocatalytic surface under UV light. Scanning electron microscopy imaging showed that the array coating consisted of closely spaced nanotubes perpendicular to the titanium plate. The aqueous solution of methyl orange was circulated through a rectangular channel flow cell containing the coated anode. The effects of electrolyte flow rate and applied potential on the oxidation rate and efficiency were evaluated. At higher mean linear flow rates, the efficiency of the oxidation process improved, indicating a mass transport-controlled process. At more positive applied potentials, the TiO2 structure deteriorated resulting in a lower oxidation efficiency.