Navegando por Palavras-chave "Adaptação fisiológica"
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- ItemSomente MetadadadosAspectos morfológicos e morfométricos do miocárdio da rata albina durante a prenhez.(Universidade Federal de São Paulo (UNIFESP), 1996) Liberatori Filho, Aroldo Walter [UNIFESP]; Simões, Manuel de Jesus [UNIFESP]
- ItemAcesso aberto (Open Access)Aspectos ultra-estruturais da fibra muscular cardíaca de ratas albinas durante o ciclo gravídico-puerperal(Associação Médica Brasileira, 1999-07-01) Liberatori Filho, Aroldo Walter [UNIFESP]; Lopes, Cleide D. [UNIFESP]; Simões, Manuel de Jesus [UNIFESP]; Mora, Oswaldo Alves [UNIFESP]; Carvalho, Antonio Carlos [UNIFESP]; Lopes, Antonio Carlos [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)PURPOSE. In the present study we evaluated the morphology of left ventricular cardiomyocytes of albino rats during pregnancy and puerperium by means of transmission electron microscopy. METHODS. Once pregnancy was confirmed, 77 rats were randomly divided in two groups, respectively, gestation (G) and puerperium ( P). The animals of the gestation group were divided into four subgroups, according to gestational age: 1st (G-A), 7th (G-B), 14th (G-C) and 21st (G-D) days of pregnancy. The group defined as puerperium was divided into three subgroups: 7th (P-A), 14th (P-B) and 21st (P-C) days of puerperium. In the end of each established period, the animals were sacrificed and fragments of the medium third of the left ventricle were resected and routinely prepared for electron microscopy analysis. RESULTS. The results obtained with transmission electron microscopy analysis revealed a gradative increase of the cardiomyocytes during pregnancy (increase of myofibrils, which are permeated by numerous mitochondria at the end of gestation). The blood capillary wall showed progressive thinning, with an increase of pynocytotic vesicles in endothelial cells, and intense sarcolemal folding at T- tubule level (capillary tunnels). In the puerperium group, there is a progressive regression in these alterations returning to pre-gestational level at the end of the puerperium cycle. These findings indicate the occurrence of hypertrophy of cardiomyocytes during pregnancy. CONCLUSION. The findings indicate the occurrence of hypertrophy of cardiomyocytes during pregnancy.
- ItemAcesso aberto (Open Access)A efetividade do treinamento auditivo formal em idosos usuários de próteses auditivas no período de aclimatização(Sociedade Brasileira de Fonoaudiologia, 2007-12-01) Miranda, Elisiane de Crestani [UNIFESP]; Andrade, Adriana Neves de [UNIFESP]; Gil, Daniela [UNIFESP]; Iorio, Maria Cecilia Martinelli [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)PURPOSE: To investigate the efficiency of a formal auditory training program in hearing aid wearers during the acclimatization period. METHODS: Eighteen subjects (mean age of 71.38 years old), male and female, binaural intra-aural hearing aid users for one week participated in the study. Experimental (with auditory training) and Control (without training) groups were formed randomly. Subjects in the experimental group have undergone a formal auditory training program organized in seven 50-minute sessions, once a week. Evaluation procedures included speech recognition tests and a self-assessment questionnaire. These procedures were carried out before (1st evaluation) and after (2nd evaluation) the training for the Experimental Group and in the Initial and Final evaluation for the Control Group. RESULTS: In the experimental group, both the word recognition score (WRS) and the speech in noise test showed significantly improved results after the training (2nd evaluation). In the study of signal-to-noise ratio for sentence recognition in noise, there was a slight tendency (p-value near 0,05) of improvement in the evaluation after the training. It was also observed that for the Experimental Group the results in the 2nd evaluation have not revealed differences in comparison to the results of the Control Group in all tests. CONCLUSION: It could be concluded that the aural rehabilitation program, including formal auditory training beneficiates the elderly in the period of hearing aids adaptation and also modifies the auditory behavior of these subjects.
- ItemAcesso aberto (Open Access)Estudo histomorfométrico dos cardiomiócitos do ventrículo esquerdo das ratas albinas durante a prenhez(Associação Médica Brasileira, 1999-07-01) Liberatori Filho, Aroldo Walter [UNIFESP]; Lopes, Renato Delascio [UNIFESP]; Mora, Oswaldo Alves [UNIFESP]; Simões, Manuel de Jesus [UNIFESP]; Lopes, Antonio Carlos [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)PURPOSE. In the present study we evaluated, by light microscopy, and throughout morphometry, whether hypertrophy of cardiac striated muscular fibers of left ventricular occur in albino rat, during pregnancy. METHODS. After maiting, 12 nuliparous rats were divided into four groups with three animals for each group. The female rats corresponding to each group were killed at 1st, 7th, 14th and 21st days of pregnancy. RESULTS. Observation, on light microscopy (H.E) had at one view, did not display any alterations during pregnancy. However, the morphometry revealed that nuclei of cardiomyocytes are augmented in volume at 14th day of pregnancy and statistically significant data show the hypertrophy. CONCLUSION. The obtained data show the existence of a dinamic and reversible process of ventricular remodelling in consequence of adaptation physiological alterations of the cardiovascular normal pregnancy.