Navegando por Palavras-chave "Administração de medicamentos"

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    Use of safety strategies to identify children for drug administration
    (Escola Paulista de Enfermagem, Universidade Federal de São Paulo (UNIFESP), 2014-01-01) Souza, Sabrina De; Rocha, Patrícia Kuerten; Cabral, Patrícia Fernanda De Almeida; Kusahara, Denise Miyuki; Universidade Federal de Santa Catarina; Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE:To understand the use of safety strategies in child identification for drug administration.METHODS:In this cross-sectional study at a pediatric unit, drugs were distributed in a centralized and unique manner. We conducted 373 observations of the process for preparing and distributing drugs carried out by 25 nursing professionals.RESULTS:The pharmacy had distributed 198 (53.1%) medicines without identifying the drugs' label, which, while in storage, was identified with the child's first name handwritten on adhesive tape. At the time of drug preparation, the professional transcribed the drug's name as described in the prescription to the drug label for 173 (90.6%) observations of injectable drug preparation and 161 (88.5%) observations of preparation of oral drugs. Information regarding the five rights of medication administration and preparation, such as the full name of the child, appeared on 10.7% of drug labels.CONCLUSION:No safety strategies to identify children during drug administration were found, nor were any standards for data identification observed.
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    Uso potencial de nanopartículas de óxido de ferro contendo DMSA como veículos magnéticos contra a doença covid-19
    (Universidade Federal de São Paulo, 2023-11-28) Martins, Elisama Silva [UNIFESP]; Ferreira, Paula Silvia Haddad [UNIFESP]; http://lattes.cnpq.br/8472122310617187; http://lattes.cnpq.br/5688741640197138
    Iron oxide magnetic nanoparticles have been employed as potential vehicles for a large number of biomedical applications, such as drug delivery. This article describes the synthesis, characterization and in vitro cytotoxic in COVID-19 cells evaluation of DMSA superparamagnetic iron oxide magnetic nanoparticles. Magnetite (Fe3O4) nanoparticles were synthesized by co-precipitation of iron salts and coated with meso-2,3-dimercaptosuccinic acid (DMSA) molecule. Structural and morphological characterizations were performed by X-ray diffraction (XRD), Fourier transformed infrared (FT-IR), magnetic measurements (SQUID), transmission electron microscopy (TEM), and dynamic light scattering (DLS). Our results demonstrate that the nanoparticles have a mean diameter of 12 nm in the solid-state and are superparamagnetic at room temperature. There is no toxicity of SPIONS-DMSA under the cells of patients with COVID-19. Taken together the results show that DMSA- Fe3O4 are good candidates as nanocarriers in the alternative treatment of studied cells.