Navegando por Palavras-chave "Biopsia de linfonodo sentinela"

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    A pesquisa do linfonodo sentinela para o câncer de mama na prática clínica do ginecologista brasileiro
    (Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, 2007-03-01) Quadros, Luis Gerk De Azevedo [UNIFESP]; Gebrim, Luiz Henrique [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Centro de Referência da Saúde da Mulher do Estado de São Paulo (Hospital Pérola Byington)
    Axillary nodal metastasis is still the most important breast cancer prognostic factor. As in approximately 80% of the patients with tumors measuring less than 2 cm the axillary lymph nodes are negative, it has been proposed sentinel lymph node biopsy, reducing surgical morbidity in the patients with negative result. Recently, this technique has been widely used in Brazil, but there are two questions that need to be answered: what is the probability of a false-negative result (not diagnosing a positive lymph node) and if the understaging by false-negative result exposes the patient to the risk of axillary recurrence or even distant metastases, due to less effective surgical and adjuvant therapy. The literature shows that the false-negative rate varies from 5 to 10%, being the surgeon's experience the major factor that contributes to improved results. Although axillary relapse is rare, it is not yet possible to evaluate the long term effect of not removing positive lymph nodes, due to short follow-up. The recommendation is that sentinel lymph node biopsy should only be performed by surgeons with experience confirmed by a low false-negative rate.