Navegando por Palavras-chave "Chemexfoliation"

Agora exibindo 1 - 2 de 2
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Electric microcurrent in the restoration of the skin undergone a trichloroacetic acid peeling in rats
    (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2004-10-01) Santos, Vilma Natividade Silva; Ferreira, Lydia Masako [UNIFESP]; Horibe, Edith Kawano [UNIFESP]; Duarte, Ivone da Silva [UNIFESP]; Regional Physiotherapy and Occupational Therapy Council; Universidade Federal de São Paulo (UNIFESP)
    PURPOSE: To investigate the influence of neuromuscular electric stimulation by microcurrent (MENS - Microcurrent Electric Neuromuscular Stimulation) in the restoration of the skin of rats undergone trichloroacetic acid (TCA). METHODS: Thirty-two hairless, male, adult rats were divided into two groups (with 16 animals each). In the Control Group (G1) the application of microcurrent was simulated 48 hours after the peeling. In the Experimental Group (G2) MENS was applied 48 hours after the TCA peeling, each 48 hours up to the Day 21, under the frequency of 0.5 Hz, intensity of 50mu A, and lasting 20 minutes. The area of the lesion was evaluated on Days 7, 14, and 21 after-peeling by the Paper Template Method, and on Day 21 the histological analysis was performed. RESULTS: On microscopy changes were seen in the fibroblasts amount and structure, and in the collagen of the experimental group, with statistically significant difference (p<0,01) CONCLUSION: MENS reduced the period of restoration of the area undergone TCA peeling in rats skin.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Tretinoin peel: a critical view
    (Soc Brasileira Dermatologia, 2017) Sumita, Juliana Mayumi; Leonardi, Gislaine Ricci; Bagatin, Edileia
    The tretinoin peel, also known as retinoic acid peel, is a superficial peeling often performed in dermatological clinics in Brazil. The first study on this was published in 2001, by Cuce et al., as a treatment option for melasma. Since then, other studies have reported its applicability with reasonable methodology, although without a consistent scientific background and consensus. Topical tretinoin is used for the treatment of various dermatoses such as acne, melasma, scars, skin aging and nonmelanoma skin cancer. The identification of retinoids cellular receptors was reported in 1987, but a direct cause-effect relation has not been established. This article reviews studies evaluating the use of topical tretinoin as agent for superficial chemical peel. Most of them have shown benefits in the treatment of melasma and skin aging. A better quality methodology in the study design, considering indication and intervention is indispensable regarding concentration, vehicle and treatment regimen ( interval and number of applications). Additionally, more controlled and randomized studies comparing the treatment with tretinoin cream versus its use as a peeling agent, mainly for melasma and photoaging, are necessary.