Navegando por Palavras-chave "Conjunctival neoplasms"

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    Melanose da margem palpebral com suspeita de malignidade: relato de caso
    (Conselho Brasileiro de Oftalmologia, 2009-10-01) Oliveira, Claudia Akemi Shiratori de; Barros, Jeison de Nadai [UNIFESP]; Souza, Simone de Biagi; Cvintal, Tadeu; Schellini, Silvana Artioli; Universidade Estadual Paulista (UNESP); Universidade Federal de São Paulo (UNIFESP); Instituto de Oftalmologia Tadeu Cvintal; IOTC
    A case of a patient with an irregular pigmented lesion of the lower eyelid margin simulating malignant tumor, which was treated based on the results of impression cytology and diagnosed by histopathological study is presented. The importance of cytological technique is emphasized as an effective and safe method that avoids unnecessary and extensive procedures.
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    Membrana amniótica na reconstrução da superfície ocular após exérese de carcinoma de células escamosas da conjuntiva
    (Conselho Brasileiro de Oftalmologia, 2008-02-01) Carvalho-rêgo, Paulo Roberto De [UNIFESP]; Gomes, José Álvaro Pereira [UNIFESP]; Ballalai, Priscilla Luppi [UNIFESP]; Cunha, Marcelo Carvalho [UNIFESP]; Sousa, Luciene Barbosa De [UNIFESP]; Erwenne, Clélia Maria [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    PURPOSE: This study was designed to evaluate the use of human amniotic membrane for ocular surface reconstruction after conjunctival squamous cell carcinoma resection. METHODS: Amniotic membrane was obtained at the time of cesarean section and was preserved at -80ºC in glycerol and cornea culture media at a ratio of 1:1. The inclusion criteria were patients presenting proliferating lesions suggestive of squamous cell carcinoma (flat or elevated white lesions resembling fish meat) that involve the conjunctiva, limbus and cornea. Eight eyes of 8 patients with conjunctival squamous cell carcinoma underwent tumor resection with amniotic membrane transplantation. Three of these cases underwent total corneal epitheliectomy and amniotic membrane transplantation associated with limbal autograft. RESULTS: Mean follow-up time was 17.8 months (range, 10-35 months). In four patients (71.4%) surgical treatment was successful, with good ocular surface stability. In two patients (28.6%) results were partially successful, with mild cicatricial alterations. One patient was excluded from the study due to aggressive tumor recurrence with intraocular invasion that needed to be removed with exenteration. CONCLUSION: This study suggests that amniotic membrane transplantation is a good alternative for ocular surface reconstruction after conjunctival squamous cell carcinoma resection.
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    Uso de mitomicina C tópico no tratamento da neoplasia intra-epitelial córneo-conjuntival e carcinoma espinocelular conjuntival: resultados preliminares
    (Conselho Brasileiro de Oftalmologia, 2003-10-01) Ballalai, Priscilla Luppi [UNIFESP]; Gomes, José Álvaro Pereira [UNIFESP]; Santos, Myrna Serapião dos [UNIFESP]; Freitas, Denise de [UNIFESP]; Erwenne, Clélia Maria [UNIFESP]; Rigueiro, Moacyr Pezati [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    PURPOSE: The purpose of this study is to evaluate the safety, efficacy and recurrence after topical use of mitomycin C (MMC) for primary or recurrent corneal-conjunctival intraepithelial neoplasia (CIN) and recurrent squamous cell carcinoma (SCC). METHODS: Two groups of patients were trated. Group 1 patients with primary or recurrent CIN were treated with topical 0.02% MMC, qid for 28 days. Group 2, patients with recurrent SCC, were treated with topical 0.02% MMC, qid for 21 to28 days. RESULTS: Eight patients with CIN and 1with SCC had a total regression of the lesion and all of them had negative control exfoliative cytology for neoplastic cells. One patient with CIN and 2 with SCC had partial regression of the lesions, which were excised surgically, and the pathology was negative for neoplasia. Side effects were transient and subsided after descontinuation of the treatment. There was no recurrence of the lesions on a mean follow-up of 24.9 months. CONCLUSION: The preliminary results of this study suggest that the use of the topical MMC is safe and efficient for the treatment of primary and recurrent CIN and recurrent SCC, although it did not prevent surgery in almost all cases of CEC. There were no recurrences during the follow-up. Further studies with more patients and longer follow-up are necessary to confirm this results.