Navegando por Palavras-chave "Correção Ligamentar"

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    Estudo randomizado, comparativo, duplo encoberto do efeito analgésico da pregabalina pré e pós-operatória para correção ligamentar artroscópica de joelho
    (Universidade Federal de São Paulo (UNIFESP), 2019-12-18) Tobias, Alexandro Ferraz [UNIFESP]; Sakata, Rioko Kimiko [UNIFESP]; Leal, Plinio da Cunha [UNIFESP]; http://lattes.cnpq.br/2150178332757393; http://lattes.cnpq.br/9796401471904195; http://lattes.cnpq.br/2023042604389377; Universidade Federal de São Paulo (UNIFESP)
    Background and Objectives: The effect of pregabalin for postoperative analgesia is controversial. There is a need to evaluate whether pregabalin promotes better pain control after anterior cruciate ligament surgery, enabling better and earlier return to activities and greater comfort for performing physical therapy. The aim of this study was to evaluate the pre and postoperative analgesic effect of pregabalin in patients undergoing arthroscopic anterior cruciate ligament correction of knee and adverse effects. Methods: The study was prospective, randomized, placebo-controlled, and double-blinded conducted with 60 patients, of both genders, with 18 years age or older, physical status ASA I or II, who underwent knee anterior cruciate ligament (ACL) correction, by arthroscopy. The participants were divided into two groups: group 1 (pregabalin) received 14 capsules with 75mg and group 2 received 14 placebo capsules and were instructed to take 1 capsule daily, starting 7 days before surgery until 7 days after. Spinal anesthesia was with 0.5% hyperbaric bupivacaine (15 mg). If analgesic supplementation was required for pain control, patients with pain intensity of 1 to 3 received iv. dipyrone 1g; with no pain control after 30min, iv. ketoprofen 100mg was administered; and if no effect after 30min, iv. tramadol 100mg; and in cases of non-pain control, iv. morphine 5mg was administered, followed by 5mg doses, until pain control. There were evaluated: pain intensity at T0 (surgery completion), after 12h, 24h, 1week, 2week, 1month and 2months, by numerical scale from zero to 10; and postoperative complementary analgesic consumption. Data were submitted to statistical analysis. Results: There was no statistically significant difference in pain intensity between the groups. Morphine consumption was lower in the pregabalin group, 12 and 24h after surgery; ketoprofen and tramadol consumption was lower after 24h in pregabalin group. The adverse effects observed were nausea, vomiting and dizziness; the last was more frequent in the pregabalin group. Conclusions: The reduced need for analgesic supplementation in pregabalin group shows that this drug promotes analgesic effect. However, the patients in pregabalin group presented more dizziness, which should be taken into consideration when it is using the drug.