Navegando por Palavras-chave "Cyclosporins"

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    Late-onset persistent retinal microvascular changes after bone marrow transplantation: 3-year follow-up
    (Conselho Brasileiro de Oftalmologia, 2002-06-01) Muccioli, Cristina [UNIFESP]; Belfort, Rubens Junior [UNIFESP]; Jorge, Rodrigo; Farah, Michel Eid [UNIFESP]; Pereira, Mauricio B.; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP); Universidade Federal do Rio de Janeiro Faculdade de Medicina Setor de Retina
    Purpose: To describe a case of persistent retinopathy after bone marrow transplantation in the absence of radiation therapy. Methods: Case Report. Results: A 42 year-old man developed bilateral visual loss 15 months after receiving a bone marrow transplant for acute leukemia. The patient was treated with a high dose of cyclosporin A and oral corticosteroids. No radiation therapy was given. Late-onset, multiple, bilateral cotton-wool spots developed 15 months after the bone marrow transplantation and still persist. After three years other cotton-wool spots arose in the absence of any immunosuppressive therapy. Conclusions: Bone marrow transplantation microvasculopathy of the retina may be related to certain combinations of chemotherapy drugs or immunosuppression itself and may persist in the absence of these immunosuppressive drugs.