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- ItemAcesso aberto (Open Access)Behavior problems and social competence in brazilian children with specific language impairment(Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, 2016) Puglisi, Marina Leite [UNIFESP]; Caceres-Assenco, Ana Manhani; Nogueira, Thays; Befi-Lopes, Debora MariaThis study aimed to investigate the behavior and social profile of Brazilian children with specific language impairment (SLI) and explore whether the severity of language deficits was associated with behavioral problems and low social competence. Twenty-four children with SLI aged from 6 to 11 years who showed substantial expressive language problems and were receiving speech-language therapy were assessed through the Child Behavior Checklist (CBCL). Children with SLI showed high rates of behavioral problems and low levels of social competence. With the exception of two subscales ("somatic" and "rule breaker"), the percentage of children with SLI at risk of behavioral problems was significantly higher than the same proportion in the general population
- ItemSomente MetadadadosControl of stress-induced acth secretion by vasopressin and crh: additional evidence(Karger, 2016) Ramos, Adriana T. [UNIFESP]; Tufik, Sergio [UNIFESP]; Troncone, Lanfranco R. P.Vasopressin and CRH have complementary roles in the secretion of ACTH following different stress modalities. The concomitant use of V-1b and CRF1 receptor antagonists completely inhibits ACTH secretion in response to different stress modalities. The combination of the CRF1 antagonist SSR125543 with the V-1b antagonist SSR149415 effectively suppressed plasma ACTH 1.30 h after injection in rats stressed by ether vapor inhalation for 1 min, restraint stress for 1 h or forced swimming for 5 min. The duration of the effect was also studied. The CRF1 antagonist effectively suppressed ACTH secretion in restraint stress, while the V-1b antagonist was effective against ether inhalation. Both antagonists were necessary to block the forced swimming stress response. SSR125543 induced a prolonged effect and can be used in a model of prolonged HPA axis blockade. (C) 2016 S. Karger AG, Basel
- ItemAcesso aberto (Open Access)Overview of the mental health system in mozambique: addressing the treatment gap with a task-shifting strategy in primary care(Univ Fed Minas Gerais, Fac Letras, 2016) dos Santos, Palmira Fortunato; Wainberg, Milton L.; Caldas-de-Almeida, Jose Miguel; Saraceno, Benedetto; Mari, Jair de Jesus [UNIFESP]Background: Mozambique has gradually changed its action on mental health (MH) from an asylum-centric care with long-term hospitalization to an innovative approach to community and primary care. Objective: To collect essential information on Mozambique's MH system for decision making, to improve quality of services delivered, update MH Strategy and Action Plan. Method: The study used the WHO-AIMS to assess MH systems including policy and legislation, organization of services, MH in primary care, human resources, public education and link with other sectors, monitoring and research. A comparative analysis was conducted to present the evolution of relevant data from 2010 to 2014. Results: There are two psychiatric hospitals in the country and beds in general hospitals. In the period, the number of beds in general hospitals remained stable (203), and the beds in psychiatric hospitals increased from 173 to 298. Mental health outpatient facilities have increased from 83 to 152. The number of psychiatrists (9 in 2010, and 10 in 2014) remained very low, with a significant increase in the number of psychologists (56-109) and occupational therapists (2-23). The number of Psychiatric Technicians has increased from 66 in 2010, to 241 in 2014. This increase allowed the mental health network to expand from 60 to 135 Districts, meaning an increase of coverage from 44 to 100 % of the country districts. Conclusion: The task-shifting strategy focused on services delivered in primary care by psychiatric technicians, mid-level professionals, allowed the expansion of mental health services for all the country districts and the reduction of treatment gap in Mozambique.
- ItemSomente MetadadadosRisk factors for recurrent wheezing - international study of wheezing in infants (eisl) phase 3(Elsevier doyma sl, 2016) Aranda, Carolina Sanchez [UNIFESP]; Wandalsen, Gustavo Falbo [UNIFESP]; Fonzar, Ligia Furtado [UNIFESP]; Dela Bianca, Ana Caroline Cavalcanti; Mallol, Javier; Solé, Dirceu [UNIFESP]Background: We aimed to identify factors associated with recurrent wheezing (RW) in infants in the first year of life living in the Southern region of Sao Paulo city and participating in the "Estudio Internacional de Sibilancias en Lactantes (EISL)" - phase 3 (P3). Methods: 1335 parents of infants who were attended in primary care health units in the Southern region of Sao Paulo city from 2009 to 2010 answered the EISL-P3 written questionnaire. The wheezing group was stratified in accordance to the frequency of wheezing episodes as occasional wheezing (OW, less than three episodes), or RW (three or more episodes). Wheezing-associated factors were evaluated using multivariate analysis and were expressed as odds ratio (OR) and 95% confidence interval (95%CI). Results: The most relevant factors related to OW were pneumonia (OR = 3.10, 95%CI=1.68-5.73), hospitalisation due to pneumonia (OR = 2.88, 95%CI = 1.26-6.56) and recurrent upper respiratory infection (URI, OR = 1.87, 95%CI = 1.25-2.81). Regarding RW, recurrent URI (OR = 5.34, 95%CI = 3.83-7.45), pneumonia (OR= 4.06, 95%CI = 2.87-5.74) and asthmatic siblings (OR= 3.02, 95%CI = 1.67-5.45) were the most significantly associated factors. Conclusions: In the present study, we found that recurrent URI, positive history of pneumonia and familiar history of asthma were the most relevant factors associated with RW. The precocious knowledge of these factors can enable the identification of the probable asthmatic infants and can improve both prevention strategies and treatment of these patients. (C) 2014 SEICAP. Published by Elsevier Espana, S.L.U. All rights reserved.
- ItemSomente MetadadadosTranslation, cultural adaptation and reproducibility of the oxford shoulder score questionnaire for brazil, among patients with rheumatoid arthritis(Associacao paulista medicina, 2016) Lima, Eider da Silva [UNIFESP]; Natour, Jamil [UNIFESP]; Moreira, Emilia [UNIFESP]; Jones, Anamaria [UNIFESP]CONTEXT AND OBJECTIVE: Although shoulder questionnaires validated for Brazil do exist, none of them are aimed at populations with rheumatic disease. We believe that the Oxford Shoulder Score (OSS) may be useful in this population. The objective of this study was to translate the OSS, adapt it to Brazilian culture and test its reproducibility. DESIGN AND SETTING: Validation study conducted in university outpatient clinics. METHODS: The OSS was translated into por by two eng teachers and was then retranslated into eng by two native eng teachers. These translations were reviewed by a committee to establish the version of OSS-Brazil to be administered to 30 patients with rheumatoid arthritis (RA) and shoulder pain, in order to test the cultural adaptation. The validity and reproducibility was tested among another 30 patients with RA and shoulder pain, of both genders and aged 18 to 65 years. The internal consistency and reproducibility were analyzed. The following instruments were evaluated: OSS-Brazil