Navegando por Palavras-chave "Early neonatal mortality"

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    Early neonatal deaths associated with perinatal asphyxia in infants >= 2500 g in Brazil
    (Soc Brasil Pediatria, 2017) Branco de Almeida, Maria Fernanda [UNIFESP]; Kawakami, Mandira Daripa [UNIFESP]; Oliveira Moreira, Licia Maria; Vaz dos Santos, Rosa Maria; Anchieta, Leni Marcia; Guinsburg, Ruth [UNIFESP]
    Objective: To assess the annual burden of early neonatal deaths associated with perinatal asphyxia in infants weighing >= 2500 g in Brazil from 2005 to 2010. Methods: The population study enrolled all live births of infants with birth weight >= 2500 g and without malformations who died up to six days after birth with perinatal asphyxia, defined as intrauterine hypoxia, asphyxia at birth, or meconium aspiration syndrome. The cause of death was written in any field of the death certificate, according to International Classification of Diseases, 10th Revision (P20.0, P21.0, and P24.0). An active search was performed in 27 Brazilian federative units. The chi-squared test for trend was applied to analyze early neonatal mortality ratios associated with perinatal asphyxia by study year. Results: A total of 10,675 infants weighing >= 2500 g without malformations died within six days after birth with perinatal asphyxia. Deaths occurred in the first 24 h after birth in 71% of the infants. Meconium aspiration syndrome was reported in 4076 (38%) of these deaths. The asphyxia-specific early neonatal mortality ratio decreased from 0.81 in 2005 to 0.65 per 1000 live births in 2010 in Brazil (p < 0.001); the meconium aspiration syndrome-specific early neonatal mortality ratio remained between 0.20 and 0.29 per 1000 live births during the study period. Conclusions: Despite the decreasing rates in Brazil from 2005 to 2010, early neonatal mortality rates associated with perinatal asphyxia in infants in the better spectrum of birth weight andwithout congenital malformations are still high, and meconium aspiration syndrome plays a major role. (c) 2017 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda.
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    Perinatal factors associated with early neonatal deaths in very low birth weight preterm infants in Northeast Brazil
    (Biomed Central Ltd, 2014-12-20) Castro, Eveline Campos Monteiro de; Leite, Alvaro Jorge Madeiro; Almeida, Maria Fernanda Branco de [UNIFESP]; Guinsburg, Ruth [UNIFESP]; Univ Fed Ceara; Universidade Federal de São Paulo (UNIFESP)
    Background: in Brazil, the prevalence of prematurity has increased in recent years and it is a major cause of death in the neonatal period. Therefore, this study aims at assessing perinatal factors associated with early neonatal deaths in very low birth weight preterm infants born in a region of Brazil with low Human Development Index.Methods: Prospective cohort study of inborns with gestational age 23(0/7)-31(6/7) weeks and birthweight 500-1499 g without malformations in 19 public reference hospitals of the state capitals of Brazil's Northeast Region. Perinatal variables associated with early neonatal death were determined by Cox regression analysis.Result: Among 627 neonates, 179 (29%) died with 0-6 days after birth. Early death was associated to: absence of antenatal steroids (HR 1.59; 95% CI 1.11-2.27), multiple gestation (1.95; 1.28-3.00), male sex (2.01; 1.40-2.86), 5th minute Apgar <7 (2.93; 2.03-4.21), birthweight <1000 g (2.58; 1.70-3.88), gestational age <28 weeks (2.07; 1.42-3.02), use of surfactant (1.65; 1.04-2.59), and non-use of a pain scale (1.89; 1.24-2.89).Conclusion: Biological variables and factors related to the quality of perinatal care were associated with the high chance of early death of preterm infants born in reference hospitals of Northeast Brazil.