Navegando por Palavras-chave "Evoked potentials, auditory"

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    Associação entre fenótipo, desempenho com próteses auditivas e genótipo da deficiência auditiva infantil em crianças com e sem alteração genética
    (Sociedade Brasileira de Fonoaudiologia, 2012-01-01) Biaggio, Eliara Pinto Vieira; Azevedo, Marisa Frasson de [UNIFESP]; Iorio, Maria Cecilia Martinelli [UNIFESP]; Svidnicki, Maria Carolina Costa Melo; Satorato, Edi Lúcia; Universidade Federal de Santa Maria Departamento de Fonoaudiologia; Universidade Federal de São Paulo (UNIFESP); Universidade Estadual de Campinas (UNICAMP)
    PURPOSE: To establish the frequency of genetic mutations related to sensorineural hearing loss (SNHL); to verify if there is association between the degree of SNHL and the presence of genetic alteration; and to verify if the Minimal Response Levels (MRL) with hearing aids vary according to the genetic alteration. METHODS: Thirty hearing aids users with ages between 8 and 111 months were evaluated. The evaluation procedures used were: pure-tone audiometry; the auditory steady state response (ASSR) on sound field, with and without hearing aids; and genetic study of the hearing loss. RESULTS: Three genetic mutations were diagnosed: 35delG, A1555G and A827G, and the children with these mutations showed higher degree of SNHL. There was no difference between the genetic patterns regarding the degree of SNHL, except for patients with A827G mitochondrial mutation, because all subjects with this mutation had profound SNHL. The difference between the MRL obtained with and without amplification, considering the presence of mutation and the degree of SNHL, was higher in children with moderate SNHL without genetic alterations, both in behavioral and electrophysiological evaluations. CONCLUSION: Genetic mutations were found in 36.7% of the sample, justifying the importance of genetic tracking in the hearing habilitation process. Children with genetic mutations showed higher degrees of hearing loss. The different mutation patterns do not directly determine the degree of hearing loss. The best thresholds with amplification were found in children with moderate hearing loss without genetic alterations.
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    Auditory Brainstem Response: reference-values for age
    (Sociedade Brasileira de Fonoaudiologia, 2014-04-01) Rosa, Luana Araujo Cruz; Suzuki, Marcia Rumi; Angrisani, Rosanna Giaffredo; Azevedo, Marisa Frasson de [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)
    PURPOSE:To study the absolute latencies of waves I , III and V and interpeak I-III , III-V and I-V of Auditory brainstem responses obtained in preterm newborns in relation to post-conceptual age, term newborns and six months of age infants, establishing reference values ​​for each age group.METHODS:Retrospective study realized through the analysis of tests performed on 80 infants divided into four groups, being the group one composed per newborns assessed between 35 and 36 weeks post-conceptual age; group two by newborns assessed between 37 and 38 weeks; group three with newborns reviewed between 39 to 40 weeks; and group four with infants evaluated with six months.RESULTS:The wave I absolute latency in the group one was 1.81 ms, decreasing to 1.79 ms in groups two and three, and to 1.70 ms in group four. The wave III latency in group one was 4.74 ms, decreasing to 4.62 ms in group two, to 4.56 ms in the group three and to 4.37 ms in the group four. The wave V latency in group one was 7.14 ms, in the group two it was 7.05 ms, in the group three 6.90 ms; and in the group four it was 6.50 ms. Interpeak latencies were also decreased in all groups.CONCLUSION:The latencies studied decreased with the increasing age and were similar values ​​with the international literature.
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    Mutações genéticas da deficiência auditiva: avaliação comportamental e eletrofisiológica da audição sem e com prótese auditiva em crianças
    (Universidade Federal de São Paulo (UNIFESP), 2011-01-26) Vieira, Eliara Pinto [UNIFESP]; Azevedo, Marisa Frasson de [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    The BMPs, the inductive proteins of bone growth since the beginning of their use have been evaluated in different experimental models aiming to determine their efficacy. We know that some substances can interfere positively or negatively when used in a systemic way or places associated with the BMP. Objective: this study objective to evaluate the possible interferences of antibiotic-therapy by using the active principle of cefazolin in an experimental model with rabbits. Methods: Two groups of female New Zealand rabbits underwent a lumbar spine inter-transverse artrodesys of segment L5-L6 using posterior approach. An homolog bone graft associated with a bio-compound (bovine BMP, 1,0mg and hydroxiapatita, 9,0mg) was used in the first group. The same procedure and bio-compound were used in the second group. However the animals were submitted to a prophylactic antibiotic-therapy with cefazolin starting two hours before the procedure and maintained for 24 hours after surgery. The animals were analyzed for 15 weeks, isolated in captivity and daily evaluated by a veterinarian under the clinical and neurological views and then euthanized, being the surgical pieces removed and submitted to a radiological and histological analysis. Results: For the first group the quantity and location of the implanted material varied among the individuals. However in most of the cases, the quantity and particles of homolog bone was insignificant and disperse along the soft tissue that covers the posterior region of the vertebrae. In the other cases, the particles with reabsorvation filled the reduced space between the transversal processes. For the second group, the quantity of material and its location also varied among the individuals. In most of the cases, several particles of homolog bone filled the space between the lateral processes whose bone neo-formation led to a trapping of these particles. All the cases showed formation in a higher or lower intensity of the cartilaginous tissue in the surface of the transverse processes. The radiological analysis showed in its relative frequency a higher frequency of complete fusion for group 2 when compared to group 1. Conclusion: Under the histological view for the model and experimental period analyzed, we inferred that, despite the fact that none of the proposed treatments had promoted a complete fusion of the vertebraes per bone tissue, the use of homolog bone + bovine BMPs associated with the use of cefazolin promoted a higher cartilaginous and bone formation with lower incidence of rejection of the material grafted in the doer area when compared to the group without the association of cefazolin. Under the radiological view, the relative analysis also showed to be superior in the group where cefazolin was used as a prophylactic antibiotic.
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    Potencial evocado auditivo cortical com estímulo simples e complexo, avaliação motora e maturidade simbólica em usuários de implante coclear
    (Universidade Federal de São Paulo (UNIFESP), 2017) Silva, Paula Botelho Da [UNIFESP]; Gil, Daniela [UNIFESP]; http://lattes.cnpq.br/6363626867862971; http://lattes.cnpq.br/3964649233477694; Universidade Federal de São Paulo (UNIFESP)
    Introduction: From the moment of conception, our organism presents a biological, organizational logic, a maturative and evolutionary calendar, also suffering from the stimulation and interaction with the environment. For the proper development of language, it is important and essential that the child develops his / her symbolic function abilities to reach the most complex levels of language. Auditory evoked potentials have been extensively studied in order to analyze the behavior of the auditory pathways before stimulation by the Cochlear Implant. Objective: To longitudinally characterize cortical auditory evoked potentials, the development of symbolic play and motor development in hearing impaired children with cochlear implants compared to their hearing peers. METHODS: Ten children of both genders, aged between two and eight years, six hearing impaired children and four audiologically normal children participated in this study. The hearing impaired children were cochlear implants users. All subjects underwent Motor Development Scale, symbolic maturity, and cortical auditory evoked potential assessments and were assessed at two times, assessment and reevaluation with a minimum of four months between evaluations. The results were analyzed statistically and compared the two evaluations in each group and between groups. Results and conclusions: There were no statistically significant differences for latency and amplitude of the different elicitor stimuli of cortical auditory evoked potential between evaluation and reevaluation for both groups. In the evaluation, the group of the hearing impaired presented greater amplitudes and latency for the eliciting stimuli of the cortical auditory evoked potential. Already in the reevaluation, the groups did not present statistical differences. The group of the hearing impaired presented a greater amplitude and latency of the cortical auditory evoked potential with speech stimulus. For the group of listeners, there was no statistical difference between the different eliciting stimuli. There was no statistical difference between evaluation and reevaluation of the symbolic maturity between groups and in each group. The group of the hearing impaired presented an improvement of the motor patterns in the reevaluation. The group of listeners presented better results in the motor evaluation when compared with the hearing impaired. The group of the hearing impaired had negative correlation in the evaluation between symbolic maturity and the latencies of cortical auditory evoked potentials. In the reevaluation there was a positive correlation between chronological age and motor age, chronological age and time of use of CI, chronological age and imitation symbolic maturity. The group of listeners did not present significant results for any variable, both in the evaluation and in the reevaluation.