Navegando por Palavras-chave "Fibrina"

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    Estudo morfológico das entero-anastomoses com suturas em pontos separados complementados com adesivo sintético ou biológico em coelho
    (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2004-08-01) Amaral, Ademir Teixeira do [UNIFESP]; Taha, Murched Omar [UNIFESP]; Fagundes, Djalma José [UNIFESP]; Simões, Manuel de Jesus [UNIFESP]; Novo, Neil Ferreira [UNIFESP]; Juliano, Yara [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    PURPOSE: The aim of the research was to verify the efficacy of the fibrin or cianoacrylate glue as coadjuvant in the intestinals anastomosis of rabbits. METHODS: Eighty rabbits, lineage New Zealand, males, adults, were submitted to enterectomy of 3cm and enteroraphy distributed in four groups: Group A (two equidistants stitches); Group B (four equidistants stitches); Group C (six equidistants stitches); Group D (eight equidistants stitches). In 14 days of observation, the animals were submitted to median laparotomy for macroscopic study of the abdominal cavity for identification and evaluation of adherence, dehiscence and fistula. The segment anastomosed was removed and was maked mould of alginate for later evaluation of the index of stenosis. The parts removed were processed for histological study and evaluation of collagen, macrofages, vessels and granulomas. RESULTS: Significant difference was not presented in the evaluation of dehiscence and fistula with the two adhesives between the four subgroups. The adherence occurred in higher number in the subgroups of the synthetical adhesive. The index of stenosis was higher in the animals of the synthetical adhesive only in the subgroups with two and eight stitches. The histological analysis showed that in all the parameters evaluated (macrofages, vessels and granulomas) did not present significant difference between the two kinds of adhesives. In relation the percentagem of collagen was verified that presented significant difference in group B in that the synthetical adhesive was smaller that the biological adhesive. CONCLUSION: The biological adhesive of fibrin show more efficacy that the synthetical adhesive as coadjunvants of suture in the intestinals anastomosis.
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    Predictive factors for anterior chamber fibrin formation after vitreoretinal surgery
    (Sociedade Brasileira de Oftalmologia, 2014-04-01) Cunha, Leonardo Provetti; Costa-cunha, Luciana Virgínia Ferreira; Costa, Carolina Ferreira; Bastos, Ronaldo Rocha; Prata, Tiago dos Santos [UNIFESP]; Monteiro, Mário Luiz Ribeiro; Universidade Federal de Juiz de Fora; Hospital de Olhos de Juiz de Fora; Universidade Federal de São Paulo (UNIFESP)
    Purpose: The aim of this study was to investigate possible predictive factors related to anterior chamber fibrin formation after vitreoretinal surgery in a large series of patients.Methods:The data of 185 eyes of 185 patients submitted to vitreoretinal surgery was reviewed. The following variables were evaluated: the postoperatively presence of fibrin, age, diabetes mellitus, the vitrectomy system gauge (20, 23 or 25 gauge), the type of vitreous substitute, the influence of prior surgical procedures and the combination with cataract extraction. To evaluate predictive factors for anterior chamber fibrin formation, univariate analysis was performed. A multivariate stepwise logistic regression model was adjusted to investigate factors associated with fibrin formation (p<0.05).Results:Fibrinoid anterior chamber reaction was found in 12 (6.4%) patients. For multivariate logistic regression analysis, balanced salt solution (BSS), the chance of fibrin occurrence was 5 times greater (odds ratio 4.83, CI 95% 1.302 - 17.892; p=0.019), while combination with phacoemulsification increased the chance of fibrin formation by 20 times (odds ratio 20, CI 95% 2.480 - 161.347; p=0.005). No significant difference was found regarding other variables.Conclusion: Anterior chamber fibrin formation is an unwanted complication after vitreoretinal surgery. Factors such as combined performance of phacoemulsification and the use of balanced salt solution as a vitreous substitute may predispose the occurrence of this complication.