Navegando por Palavras-chave "Hipopotassemia"
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- ItemSomente MetadadadosAlteracoes clinicas-laboratoriais da sindrome de Bartter(Universidade Federal de São Paulo (UNIFESP), 2009) Maia, Marta Liliane de Almeida [UNIFESP]
- ItemAcesso aberto (Open Access)Influência do veículo na eficácia da reposição de potássio em ratos hipocalêmicos(Sociedade Brasileira de Cirurgia Cardiovascular, 2009-09-01) Petenusso, Márcio; Valenti, Vitor Engrácia [UNIFESP]; Abreu, Luiz Carlos de; Colombari, Eduardo [UNIFESP]; Fonseca, Fernando Luiz Affonso [UNIFESP]; Sato, Monica Akemi; Universidade Federal de São Paulo (UNIFESP); Faculdade de Medicina do ABC Departamento de FisiologiaINTRODUCTION: Patients who undergo cardiac surgery are commonly treated with diuretic therapy for the management of volume overload. The concern of hypokalemia important in the adult population submitted to cardiac surgery has been described. Intravenous potassium (K+) replacement dilution is only recommended with sodium chloride 0.9% solution (SF0.9%), likely due to the putative effects of glucose solution 5% (SG5%) on insulin secretion, which influence K+ replacement quality. However, it is not yet experimentally proved the influence of SF0.9% and SG5% on K+ replacement quality. Objectives: To evaluate the effects of different vehicles of K+ replacement on blood K+ levels in furosemide hypokalemic rats. METHODS: Male Wistar rats divided into four groups: K+SF, K+SG, SF and SG. Jugular vein cannulation for K+ replacement and femoral vein cannulation for blood analysis. Furosemide (50mg/kg) to induce hypokalemia. We prepared the following solutions: vehicle 1.6mL (SF0.9% or SG5%) + 0.4 mL de K+ (19.1%) and for control groups only vehicle 2 mL. Furosemide (50 mg/kg) was used to induce hypokalaemia, it was analyzed potassium plasmatic levels 24 hours before furosemide injection, 24 hours after furosemide injection and 30 minutes after post-replacement. RESULTS: There was no significative difference in blood K+ levels before furosemide administration, after hypokalemic induction and after K+ replacement among all groups. Only SF+K presented blood Na+ levels increaseafter K+ replacement (P<0.05). CONCLUSION: K+ replacement in different vehicles did not affect blood K+ levels in rats
- ItemSomente MetadadadosParalisia periódica: estudo de vinte pacientes(Universidade Federal de São Paulo (UNIFESP), 1993) Tengan, Celia Harumi [UNIFESP]; Gabbai, Alberto Alain [UNIFESP]