Navegando por Palavras-chave "MRI morphometric analyses"
- ItemSomente MetadadadosMorphometric MRI features are associated with surgical outcome in mesial temporal lobe epilepsy with hippocampal sclerosis(Elsevier Science Bv, 2017) Fernandes Castilho Garcia, Maria Teresa [UNIFESP]; Gaca, Larissa Botelho [UNIFESP]; Sandim, Gabriel Barbosa [UNIFESP]; Assuncao Leme, Idaiane Batista; Carrete Junior, Henrique [UNIFESP]; Centeno, Ricardo Silva [UNIFESP]; Sato, Joao Ricardo; Targas Yacubian, Elza Marcia [UNIFESP]Purpose: Corticoamygdalohippocampectomy (CAH) improves seizure control, quality of life, and decreases mortality for refractory mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS). One-third of patients continue having seizures, and it is pivotal to determine structural abnormalities that might influence the postoperative outcome. Studies indicate that nonhippocampal regions may play a role in the epileptogenic network in MTLE-HS and could generate seizures postoperatively. The aim of this study is to analyze areas of atrophy, not always detected on routine MRI, comparing patients who became seizure free (SF) with those non seizure free (NSF) after CAH, in an attempt to establish possible predictors of surgical outcome. Methods:105 patients with refractory MTLE-HS submitted to CAH (59 left MTLE