Navegando por Palavras-chave "MSE"

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    Efeito do hormônio luteinizante (LH) adicionado ao estímulo ovariano no perfil lipídico do líquido folicular de mulheres em tratamento para infertilidade
    (Universidade Federal de São Paulo (UNIFESP), 2013-07-31) Costa, Livia do Vale Teixeira da [UNIFESP]; Fraietta, Renato Fraietta [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Objectives: Using Lipidomics approach to identify the follicular fluid lipid profile of women submitted to different ovarian stimulation protocols for in vitro fertilization treatments. Method: We conducted the study using 28 self-paired samples of follicular fluid from women who presented only tubal factor as a cause of female infertility. The patients were divided into (i) FSH group, consisting of 14 patients who received FSH hormone during controlled ovarian stimulation, and (ii) FSH + LH group, composed of the same 14 patients who have returned to the sector of Assisted Human Reproduction to receive a new stimulus, which corresponded to the addition of LH to the previous protocol. Lipidomics analysis was performed by MSE mass spectrometry. Possible lipids were identified by the software SimLipid 3.4. Results: Clinical data analysis showed that there are no statistically significant differences between groups. Lipids were identified in relation to their groups, so that in the FSH group we found wax monoesters, anthocyanidins and CoA fatty acyls, while in FSH + LH group we found sphingomyelin. Conclusion: Differences were found between the two groups concerning lipid profiles analyzed in follicular fluid. These findings contributed to deepen the understanding of the molecular mechanisms involved in the administration of different hormonal stimuli for patients undergoing treatments for infertility, and so to the establishment of the best protocol for each women considering the identification of potential biomarkers.
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    As possíveis causas da infração na adolescência: para além do socialmente imposto
    (Universidade Federal de São Paulo (UNIFESP), 2018) Miguel, Gabriela de Doná Vieira [UNIFESP]; Estevão, Ana Maria Ramos [UNIFESP]; http://lattes.cnpq.br/2205537046844581; Universidade Federal de São Paulo (UNIFESP)
    Este trabalho de conclusão de curso tem como objeto de estudo as possíveis causas que levam os adolescentes a cometer atos infracionais, além das condições socioeconômicas, impostas pela sociedade. Além de ser uma breve passagem histórica sobre as políticas assistenciais para adolescentes e definição de adolescência e ato infracional, a pesquisa busca explicitar os 6 tipos de medidas socioeducativas. O olhar do profissional para esses adolescentes e quais as possibilidades a serem desconstruídas esuas outras perspectivas de vida também estarão no horizonte deste trabalho.