Navegando por Palavras-chave "Mitosis"

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    Mitose como fator prognóstico para biópsia de linfonodo sentinela em melanoma fino
    (Sociedade Brasileira de Dermatologia, 2011-08-01) Oliveira Filho, Renato Santos de [UNIFESP]; Jorge, Mayra Calil; Oliveira, Daniel Arcuschin de; Oliveira, Renato Leão de; Queiroz, Maria do Carmo Assunção; Nahas, Fabio Xerfan [UNIFESP]; Hospital Israelita Albert Einstein; Universidade Estadual Paulista (UNESP); Universidade Anhembi Morumbi; Santa Casa de Misericórdia de Votuporanga; Laboratório LOCUS Laboratório de Anatomia Patológica; Universidade Federal de São Paulo (UNIFESP)
    23-year-old female patient, with superficial spreading melanoma (SSM) on the back, Breslow 0.35 mm, Clark II, without ulceration and with 2 mitosis/mm². Patient was submitted to margin enlargement and sentinel biopsy of 2 lymph nodes (left armpit). Histopathology revealed micrometastasis in the subcapsular sinus of both. Following the recommendation of the 2009 American Joint Committee on Cancer Melanoma Staging (AJCC), the patient underwent complete axillary lymphadenectomy. No other lymph nodes were metastatic. The clinical application of dermoscopy has enabled more accurate diagnosis of cutaneous melanoma, probably contributing to a greater proportion of thin melanomas at diagnosis. The mitotic rate was included as an important prognostic factor for thin melanomas by the AJCC, suggesting biopsy for these patients