Navegando por Palavras-chave "Phaeohyphomycosis"
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- ItemAcesso aberto (Open Access)Feohifomicosis causada por Colletotrichum gloeosporioides y Alternaria infectoria en un paciente trasplantado renal(Soc Chilena Infectologia, 2014-08-01) Ogawa, Marilia Marufuji [UNIFESP]; Reis, Viviane [UNIFESP]; Godoy, Patricio [UNIFESP]; Menezes, Fernando Gatti de [UNIFESP]; Enokihara, Mílvia Maria Simões e Silva [UNIFESP]; Tomimori, Jane [UNIFESP]; Univ Austral Chile; Universidade Federal de São Paulo (UNIFESP); Dept MedSeveral species of black fungi have been reported as agents of subcutaneous phaeohyphomycosis. Although most of these fungi are considered opportunistic pathogens, they play an important role in phaeohyphomycosis, a disease considered an emergent mycosis among solid organ recipients. We report a case of phaeohyphomycosis caused by Alternaria infectoria of the left hand and the 4th finger of the right hand of a 68-year-old male who underwent a renal transplant 35 months before. The lesion was treated with surgical excision. One year later, the patient presented a new lesion on the 5th finger of the right hand, but this time caused by Colletotrichum gloeosporioides that was also removed surgically. Both lesions did not relapse after being removed. Antifungal susceptibility testing was performed against five antifungal drugs (amphotericin B, itraconazole, flucytosine, fluconazole and voriconazole). Alternaria infectoria was resistant to all five drugs and C. gloeosporioides was sensitive only to amphotericin B and voriconazole. We emphasize the need of histopathologic and microbiologic studies of new lesions of phaeohyphomycosis, since in this case the same patient was infected twice by two different fungi.
- ItemSomente MetadadadosMelanized fungal infections in kidney transplant recipients: contributions to optimize clinical management(Elsevier Sci Ltd, 2017) Santos, D. W. [UNIFESP]; Camargo, L. P. [UNIFESP]; Goncalves, S. S. [UNIFESP]; Ogawa, M. M.; Tomimori, J. [UNIFESP]; Enokihara, M. M.; Medina-Pestana, J. O.; Colombo, A. L. [UNIFESP]Objectives: This is a retrospective and observational study addressing clinical and therapeutic aspects of melanized fungal infections in kidney transplant recipients. Methods: We retrospectively reviewed medical records of all patients admitted between January 1996 and December 2013 in a single institution who developed infections by melanized fungi. Results: We reported on 56 patients aged between 30 and 74 years with phaeohyphomycosis or chromoblastomycosis (0.54 cases per 100 kidney transplants). The median time to diagnosis post-transplant was 31.2 months. Thirty-four (60.8%) infections were reported in deceased donor recipients. Fifty-one cases of phaeohyphomycosis were restricted to subcutaneous tissues, followed by two cases with pneumonia and one with brain involvement. Most dermatological lesions were represented by cysts (23/51