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- ItemAcesso aberto (Open Access)Plakilactone J: Structure and absolute configuration(Elsevier, 2022-11-12) Batista, Andrea Nastri de Luca; Brito, Mateus de Freitas; Batista Junior, João Marcos [UNIFESP]; Valverde, Alessandra Leda; http://lattes.cnpq.br/4209224090500050The chemical investigation of the Brazilian marine sponge Plakortis angulospiculatus led to the isolation of the new peroxide-derived polyketide plakilactone J (1). The structure of (-)-1 was established by means of HRMS and NMR analysis, while its absolute configuration was unambiguously determined as (4R,6R) by vibrational circular dichroism spectroscopy and density functional theory calculations.