Navegando por Palavras-chave "Respiratory Sounds"

Agora exibindo 1 - 3 de 3
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Prevalência de sibilância e fatores de risco associados em crianças no primeiro ano de vida, residentes no Município de Recife, Pernambuco, Brasil
    (Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, 2011-08-01) Medeiros, Decio; Silva, Almerinda Rêgo; Rizzo, José Ângelo; Sarinho, Emanuel; Mallol, Javier; Solé, Dirceu [UNIFESP]; Universidade Federal de Pernambuco; Universidad de Santiago de Chile; Universidade Federal de São Paulo (UNIFESP)
    The aim of this study was to verify the prevalence of wheezing in infants (< 1 year of age) in Recife, Pernambuco State, Brazil, and to identify associated risk factors. Sample and methods: the study was performed according to the protocol of the International Study of Wheezing in Infants (EISL) in children ranging from 12 to 15 months of age. The sample was analyzed for presence or absence of wheezing. A total of 1,071 parents of children ranging from 12 to 15 months of age were interviewed. Prevalence of wheezing in the first year of life was 43%, with no difference between the sexes. Wheezing in the first year of life was associated with pneumonia, family history of asthma, more than nine episodes of upper airway infection, and the first cold before six months of age (p < 0.001). Prevalence of wheezing in the first year of life was high in Recife. Early onset (and high number) of colds, family history of asthma, and pneumonia were associated with wheezing in these children.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Prevalência e fatores de risco para sibilância recorrente em lactentes de 12 a 15 meses na cidade de Cuiabá-MT, Brasil
    (Universidade Federal de São Paulo (UNIFESP), 2019-08-05) Juca, Sileyde Cristiane Bernardino Matos Povoas [UNIFESP]; Sole, Dirceu [UNIFESP]; http://lattes.cnpq.br/8188258243306974; http://lattes.cnpq.br/8321105312040587; Universidade Federal de São Paulo (UNIFESP)
    Objectives: To evaluate the prevalence of recurrent wheezing in infants in the city of Cuiabá-MT. To identify the factors associated with wheezing in the life’s first year. To verify the temporal trend in the epidemiology of wheezing in infants’ life’s first year. To identify passive smoking in infants with recurrent wheezing by urinary cotinine. Methods: Cross-sectional study of infants’ population base from 12 to 15 months using the standardized questionnaire from the Estudio Internacional de Sibilancias en Lactantes (EISL). The parents and/or guardians answered to the questionnaire during the visits to the Basic Health Units for routine visits and/or immunization or during home routine visits performed by health agents. For the evaluation of the temporal trend, the results found were compared to those previously obtained by a study performed between 2009 and 2010 in the same center and using the same method. Passive smoking was evaluated by the cotinine’s dosage in a urine sample. Results: A total of 1,066 infants, mostly male gender (N=539, 50.6%) and white race (N=456, 42.8%) participated in the study. 476 (44.7%) infants who participated in the study had at least one episode of wheezing in the first year of life, with the beginning’s average age of 6.6 months (±3 months) and significant male’s gender predominance. The prevalence of occasional wheezing (OW, less than three episodes) and recurrent wheezing (RW, up to three episodes) was 21.1% and 23.5%, respectively, which being the last one significantly higher in male gender (62.9%). Frequent nocturnal awakening (28.3%), perception of lack of air by parents (52.2%), emergency room visits (72.9%), hospitalization for wheezing (39.8%), use of beta agonist (88.4%) and oral corticosteroid (63.0%) were significantly higher in RW. The medical asthmas diagnosis (16.8%) and pneumonia diagnosis (46.2%) were higher in infants with RW. The main risk factors associated with wheezing in the first year were: smoking during pregnancy (OR=2.93; 95%CI=1.63-5.26); family income less than R$ 800.00 (OR=2.23, 95%CI=1.03-4.62); use of antibiotics in the first year (OR=1.95, 95%CI=1.42-2.67); first episode of airway infection before three months of life (OR=1.78, 95%CI=1.20-2.65); pneumonia hospitalization (OR=1.72, 95%CI=1.20-2.25); having siblings with asthma (OR=1.68, 95%CI=1.04-2.71), among others. The comparison between the two studies (2009-10 vs. 2016-17) showed elevated rates: wheezing ever, 27.7% vs. 44.7%, p<0.00; WO, 15.0% vs. 21.1%, p<0.00; and RW, 12.7% vs. 23.5%, p<0.00; significant increase also occurred in medical asthma diagnosis (9.5% vs. 16.8%, p<0.00). The mean cotinine level found among passive smokers was 32.4±8.6 ng/ml and the prevalence of passive smoking was 32.8%, being significantly higher among wheezing infants compared to those not exposed infants (41.8 % vs. 24.3%; p<0.030), especially in RW (63.2% vs. 20.7%; p<0.001). Conclusions: The prevalence of wheezing and RW in infants in their life’s first year was high and there was a significant increase over the years, associated with increased morbidity. Some of the factors which were found associated with wheezing in the first year of life are also associated with the development of asthma in children and adolescents. The evaluation of urinary cotinine levels proved to be a good marker for assessing exposure to cigarette smoke.
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Risk factors for recurrent wheezing - international study of wheezing in infants (eisl) phase 3
    (Elsevier doyma sl, 2016) Aranda, Carolina Sanchez [UNIFESP]; Wandalsen, Gustavo Falbo [UNIFESP]; Fonzar, Ligia Furtado [UNIFESP]; Dela Bianca, Ana Caroline Cavalcanti; Mallol, Javier; Solé, Dirceu [UNIFESP]
    Background: We aimed to identify factors associated with recurrent wheezing (RW) in infants in the first year of life living in the Southern region of Sao Paulo city and participating in the "Estudio Internacional de Sibilancias en Lactantes (EISL)" - phase 3 (P3). Methods: 1335 parents of infants who were attended in primary care health units in the Southern region of Sao Paulo city from 2009 to 2010 answered the EISL-P3 written questionnaire. The wheezing group was stratified in accordance to the frequency of wheezing episodes as occasional wheezing (OW, less than three episodes), or RW (three or more episodes). Wheezing-associated factors were evaluated using multivariate analysis and were expressed as odds ratio (OR) and 95% confidence interval (95%CI). Results: The most relevant factors related to OW were pneumonia (OR = 3.10, 95%CI=1.68-5.73), hospitalisation due to pneumonia (OR = 2.88, 95%CI = 1.26-6.56) and recurrent upper respiratory infection (URI, OR = 1.87, 95%CI = 1.25-2.81). Regarding RW, recurrent URI (OR = 5.34, 95%CI = 3.83-7.45), pneumonia (OR= 4.06, 95%CI = 2.87-5.74) and asthmatic siblings (OR= 3.02, 95%CI = 1.67-5.45) were the most significantly associated factors. Conclusions: In the present study, we found that recurrent URI, positive history of pneumonia and familiar history of asthma were the most relevant factors associated with RW. The precocious knowledge of these factors can enable the identification of the probable asthmatic infants and can improve both prevention strategies and treatment of these patients. (C) 2014 SEICAP. Published by Elsevier Espana, S.L.U. All rights reserved.