Navegando por Palavras-chave "Rosacea"

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    Ocular rosacea: a review
    (Conselho Brasileiro de Oftalmologia, 2012-10-01) Vieira, Ana Carolina Cabreira [UNIFESP]; Hofling-Lima, Ana Luisa [UNIFESP]; Mannis, Mark J; Universidade Federal de São Paulo (UNIFESP); University of California Department of Ophthalmology
    Rosacea is a prevalent chronic cutaneous disorder with variable presentation and severity. Although considered a skin disease, rosacea may evolve the eyes in 58-72% of the patients, causing eyelid and ocular surface inflammation. About one third of the patients develop potentially sight-threatening corneal involvement. Untreated rosacea may cause varying degrees of ocular morbidity. The importance of early diagnosis and adequate treatment cannot be overemphasized. There is not yet a diagnostic test for rosacea. The diagnosis of ocular rosacea relies on observation of clinical features, which can be challenging in up to 90% of patients in whom accompanying roseatic skin changes may be subtle or inexistent. In this review, we describe the pathophysiologic mechanisms proposed in the literature, clinical features, diagnosis and management of ocular rosacea, as well as discuss the need for a diagnostic test for the disease.
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    Questionário de qualidade de vida específico para Rosácea: tradução, adaptação cultural e validação para o Português do Brasil
    (Universidade Federal de São Paulo (UNIFESP), 2017-07-31) Tannus, Flavia Cisi [UNIFESP]; Bagatin, Edileia [UNIFESP]; http://lattes.cnpq.br/6478900066830476; http://lattes.cnpq.br/6544586313020344; Universidade Federal de São Paulo (UNIFESP)
    Aim: translation into Brazilian Portuguese, development of cultural adaptation and validation of the RosaQoL disease-specific questionnaire through the participation of individuals that were diagnosed with Rosacea of any subtype. Methods: recommended procedures for translation, cultural adaptation and validation of an instrument were followed, and three interviews were performed: baseline (n = 60); second (from 7 to 14 days after baseline, n=46) and third (from four to six months after baseline, n=38). In the first one, the SF-36 and RosaQoLBR (Brazil) were applied, in the others only RosaQoL-BR. Psychometric measures were analyzed: reliability by internal consistency (Cronbach’s alpha); test-retest reproducibility (intraclass correlation coefficient); responsiveness by the Wilcoxon test, comparing the interviews and third and validity, by correlations, comparative analysis and variance. Results: terms of the original questionnaire were replaced to guarantee cultural and semantic equivalence. The validity can be demonstrated by the expressive correlations between the RosaQoL-BR domains and significance in the Jonckheere-Terpstra test (p< 0.05) between the scores of the RosaQoL-BR domains and the self-perception of the participants in relation to the disease. Reliability was acceptable; alpha coefficient ranged from 0.923 to 0.916 in the first and second applications of the RosaQoL-BR, respectively, and the Intraclass Correlation Coefficient (ICC) ranged from 0.671 to 0.863 in the range of seven to fourteen days. Responsiveness, measured by the formation of three groups of participants based on self-perception of rosacea (better, worse, or unchanged), was found to be significant in the "best" response group (p< 0.05). Limitations: small sample; clinical variability of rosacea due to the few sources of screening of participants. Conclusions: RosaQoL-BR has been shown to be a reliable, valid and responsive questionnaire for individuals with any subtype of rosacea, with limitations.