Navegando por Palavras-chave "Semantic memory"
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- ItemSomente MetadadadosAssessment of working memory in patients with mesial temporal lobe epilepsy associated with unilateral hippocampal sclerosis(Elsevier B.V., 2010-07-01) Silva Tudesco, Ivanda de Souza [UNIFESP]; Vaz, Leonardo Jose [UNIFESP]; Silva Mantoan, Marcele Araujo [UNIFESP]; Belzunces, Erich [UNIFESP]; Noffs, Maria Helena [UNIFESP]; Sales Ferreira Caboclo, Luis Otavio [UNIFESP]; Targas Yacubian, Elza Marcia [UNIFESP]; Sakamoto, Americo Ceiki [UNIFESP]; Amodeo Bueno, Orlando Francisco [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Objective: the aim of the present study was to investigate whether working memory is impaired in mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS), a controversial and largely unexplored matter.Methods: Twenty subjects with left MTLE-HS, 19 with right MTLE-HS, and 21 control right-handed subjects underwent neuropsychological assessment of episodic and semantic memory, executive functions, and specific working memory components.Results: Left and right epileptogenic foci resulted in impairment of verbal and nonverbal episodic memory (verbal memory deficit greater in left MTLE-HS than in right MTLE-HS). in addition, patients with left MTLE-HS were impaired in teaming paired associates, verbal fluency, and Trail Making. No differences were seen in the tests carried out to evaluate the working memory components (except visuospatial short-term memory in right MTLE-HS).Conclusion: in this study we did not detect reliable working memory impairment in patients with MTLE-HS with either a left or right focus in most tasks considered as tests of working memory components. (C) 2010 Elsevier Inc. All rights reserved.