Navegando por Palavras-chave "Tendon"

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    Fotobiomodulação associada ao tratamento conservador, na fase inicial, de pacientes com ruptura aguda do tendão do calcâneo: ensaio clínico randomizado duplo-cego
    (Universidade Federal de São Paulo (UNIFESP), 2019-04-15) Oliveira, Pedro Rizzi de [UNIFESP]; Pinfildi, Carlos Eduardo [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Introduction: The Achilles tendon is the most affected by tendon ruptures, which is commonly related to sports practice. Immobilization in the conservative treatment leads to disorders on tendon tissue that can interfere in the tendon repair. Photobiomodulation (PBM) has been shown to be effective in promoting tissue repair and reducing the damages caused by immobilization. Objectives: Assess the effects of PBM associated with conservative treatment of patients with acute Achilles tendon rupture. Methods: Twenty-two male subjects, age between 18-65 years, with a diagnosis of acute rupture of the unilateral Achilles tendon performed by the Thompson test were included. Participants were randomly allocated into two groups: Control Group (CG) and Photobiomodulation Group (PBMG). Both groups underwent through a plaster immobilization protocol for 8 weeks. During this period, PBMG was submitted to 16 sessions of photobiomodulation (cluster 904nm, 858nm and 658nm) with the energy of 5 J per point and CG to a sham treatment. After the end of the plaster protocol both groups were submitted to the same protocol of rehabilitation for eight weeks, including strengthening exercises, proprioception and range of motion gain (ROM). The assessments were performed on 8th, 12th and 16 weeks, using the ATRS questionnaire, isometric dynamometry for plantar flexion, numeric pain scale (NPS) and goniometry of ankle joint. Results: Statistical difference (p <0.01) was found in favor of the PBMG in the NPS perceived in physical activity in the 12th week. No statistical differences were found in the ATRS questionnaire, muscle strength, ankle ROM. Conclusion: PBM did not has an effect on function, measured trough ATRS; FBM had an influence in reducing pain perceived at effort of patients with ruptured tendon of the calcaneus.
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    Structural and biochemical alterations during the healing process of tendons treated with Aloe vera
    (Elsevier B.V., 2012-10-29) Aro, A. A.; Nishan, U. [UNIFESP]; Perez, M. O.; Rodrigues, R. A.; Foglio, M. A.; Carvalho, J. E.; Gomes, L.; Vidal, B. C.; Pimentel, E. R.; Universidade Estadual de Campinas (UNICAMP); Universidade Federal de São Paulo (UNIFESP)
    Aims: the tendon is composed of highly organized collagen fibers that form a complex supramolecular structure. After lesions, the organization and composition of the tendon are not completely restored. Our purpose was to evaluate if the application of Aloe vera improves tendon healing, considering the effectiveness in the stimulus of collagen synthesis.Main methods: the calcaneal tendon of male Wistar rats was partially transected with subsequent topical application of A. vera ointment at the injury. the animals were separated into groups with tendons treated with the A. vera extract for 7 days and excised on the 7th, 14th and 21st days after surgery: control rats received only ointment base without plant extract.Key findings: Morphological analysis using polarization microscopy showed that the entire tendon undergoes a remodeling process, with disorganized collagen fibers by days 7 and 14 in plant treated and non-treated groups and with a higher birefringence in tendons of the plant-treated group on the 21st day. A higher concentration of hydroxyproline was found in plant-treated tendons on days 7 and 14 compared with their controls. Western blots showed lower amounts of type I collagen in the plant-treated group on day 14 compared with the control. MMP-9 diminished 14 days after lesion and the active isoform of MMP-2 increased on day 21 in plant-treated groups.Significance: the present study indicates a beneficial effect of A. vera in the tissue reorganization in the transected region of the tendon 21 days after injury and is supported by an increase of active MMP-2. (C) 2012 Elsevier Inc. All rights reserved.