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- ItemEmbargoAchados clínicos e polissonográficos de pacientes com bócio volumoso submetidos à tireoidectomia(Universidade Federal de São Paulo (UNIFESP), 2010-06-30) Haddad, Leonardo [UNIFESP]; Abrahão, Marcio [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Objective: To evaluate the prevalence of the syndrome of obstructive sleep apnea (OSA) in a group of patients with large goiter and determine the impact of thyroidectomy on clinical, anthropometric and polysomnographic findings. Method: 24 patients with euthyroid goiter within volume exceeding 100 ml were included. Patients were subjected to physical examination, sleep questionnaires and baseline polysomnography performed in a sleep laboratory. Following this assessment patients were referred for thyroidectomy, and three months after surgery, were again subjected to the same initial protocol. After data collection the patients were divided into two groups, one with OSA and another group without OSA (NOSA). The anthropometric, clinical and polysomnography parameters found preoperatively were compared to the same findings postoperatively, both in whole group (OSA + NOSA), and in the group with OSA only. Results: 70.8% of patients have OSA (p = 0.004). After thyroidectomy as data found statistically significant: (a) lower neck circumference postoperatively in both the whole group, as in the OSA group, (2) Postoperative improvement in the Epworth Sleepiness Scale, score for quality of sleep and Berlin questionnaire suggestive of OSA in both the whole group and in the OSA group, (3) Reduction of postoperative sleep N1 of the whole group. Data without statistical significance: (4) Body mass index in both the whole group, as in the OSA group, (5) Complaint of habitual snoring in both the whole group, as in the OSA group, (6) All polysomnographic parameters (except N1 for the whole group) in both the whole group, as in the OSA group. Conclusion: There is a high prevalence of OSA in patients with large goiter. After thyroidectomy there is an improvement of subjective parameters related to sleep (sleep questionnaires), which is not observed for the objective polysomnographic parameters.