Navegando por Palavras-chave "Vasos Linfáticos"

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    Sentinel lymph node biopsy in cutaneous melanoma
    (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2007-10-01) Oliveira, Andrea Fernandes de [UNIFESP]; Santos, Ivan Dunshee de Abranches Oliveira [UNIFESP]; Tucunduva, Thaís Cardoso de Mello [UNIFESP]; Sanches, Luciana Garbelini [UNIFESP]; Oliveira Filho, Renato Santos de [UNIFESP]; Enokihara, Mílvia Maria Simões e Silva [UNIFESP]; Ferreira, Lydia Masako [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    PURPOSE: To assess the importance of sentinel lymph node biopsy in patients with cutaneous melanoma. METHODS: Ninety consecutive non-randomized patients with stages I and II melanoma who underwent sentinel lymph node biopsy were followed up prospectively for six years. RESULTS: Patients were followed up for a mean period of 30 months. Their mean age was 53.3 years, ranging from 12 to 83 years. Thirty patients were male (37.5%) and 50, female (62.5%). Sentinel lymph node was positive in 32.5% and negative in 67.5%. It was found that the thicker the tumor, the greater the incidence of positive sentinel lymph nodes. In the group of patients with positive sentinel lymph nodes, recurrence occurred in 43.5%, but in those with negative sentinel lymph nodes, in only 7%, what points out to the association of tumor recurrence and positive sentinel lymph nodes. There were no major postoperative complications. CONCLUSION: Sentinel lymph node biopsy was demonstrated to be a safe method for selecting patients who need therapeutic lymphadenectomy.
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    Vital dye is enough for inguinal sentinel lymph node biopsy in melanoma patients
    (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2006-02-01) Oliveira Filho, Renato Santos de [UNIFESP]; Silva, Allisson Monteiro da [UNIFESP]; Hochman, Bernardo [UNIFESP]; Oliveira, Renato Leão de; Arcuschin, Liliana; Wagner, Jairo; Yamaga, Lílian Yuri; Ferreira, Lydia Masako [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Oncology Prevention Center; Albert Einstein Hospital Nuclear Medicine Service
    PURPOSE: The importance of gamma probe detection (GPD) combined with vital dye for sentinel node (SN) biopsy is well accepted. We evaluated the efficacy of patent blue dye (PBD) in identifying inguinal SN. METHODS: Ninety-four cutaneous melanoma patients with inferior extremity lesions were submitted to SNB according to a established protocol. Patients were randomized in two groups: Blue group, where SN was identified by PPD and Probe group, where SN was identified by GPD. The median age was 44.2 years and median Breslow thickness was 2.1 mm. Preoperative lymphoscintigraphy, lymphatic mapping with PBD and intra-operative GPD was performed on all patients. Histological examination of SN consisted of hematoxylin-eosin and immunohistochemical staining. If micrometastases were present complete lymphadenectomy was performed. The SN was considered as identified by PBD if it was blue and identified by GPD if it demonstrated at least ten times greater radioactivity than background. RESULTS: It was explored 94 inguinal lymphatic basins, 145 SN were excised (70 guided primarily by blue dye and 75 guided primarily by probe). All SN identified by preoperative lymphoscintigraphy were excised. In the Blue group PPD identified all SN and all of them were hot. In the Probe group all SN were identified by probe and were blue. The coincidence of PPD and GPD was 100%. CONCLUSION: Patent blue dye is enough to identify superficial inguinal SN in cutaneous melanoma.