Navegando por Palavras-chave "Whole-genome sequencing"

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    Draft genome sequence of a multidrug-resistant Aeromonas hydrophila ST508 strain carrying rmtD and bla(CTX-M-131) isolated from a bloodstream infection
    (Elsevier Sci Ltd, 2017) Moura, Quezia; Fernandes, Miriam R.; Cerdeira, Louise; Santos, Ana Carolina M. [UNIFESP]; de Souza, Tiago A.; Ienne, Susan; Pignatari, Antonio Carlos C. [UNIFESP]; Gales, Ana C. [UNIFESP]; Silva, Rosa M. [UNIFESP]; Lincopan, Nilton
    Here we report the draft genome sequence of a multidrug-resistant (MDR) Aeromonas hydrophila strain belonging to sequence type 508 (ST508) isolated from a human bloodstream infection. Assembly and annotation of this draft genome resulted in 5 028 498 bp and revealed the presence of 16S rRNA methylase rmtD and bla(CTX-M-131) genes encoding high-level resistance to aminoglycosides and cephalosporins, respectively, as well as multiple virulence genes. This draft genome can provide significant information for understanding mechanisms on the establishment and treatment of infections caused by this pathogen. (C) 2017 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.