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- ItemAcesso aberto (Open Access)Correlação entre sinais e sintomas de olho seco em pacientes portadores da síndrome de Sjögren(Conselho Brasileiro de Oftalmologia, 2008-08-01) Barboza, Marcello Novoa Colombo; Barboza, Guilherme Novoa Colombo; Melo, Gustavo Mendonça de; Sato, Elcio Hideo [UNIFESP]; Dantas, Maria Cristina Nishiwaki; Dantas, Paulo Elias Correa; Felberg, Sérgio; Santa Casa de Misericórdia de São Paulo; Universidade Federal de São Paulo (UNIFESP); Santa Casa de Misericórdia de São Paulo Departamento de OftalmologiaPURPOSE: To study the correlation between the signals and symptoms of dry eye in Sjögren's syndrome patients. METHODS: We formed the case group with 17 Sjögren's syndrome patients and the control group with 25 normal patients. For evaluation of the symptoms the Ocular Surface Disease Index (OSDI) questionnaire was applied to both groups and, after that, all the individuals were submitted to the ocular tests: Schirmer I and II, coloration of the ocular surface with rose bengal, pachymetry and esthesiometry. Spearman's correlation test was used to analyze the correlations between signals and symptoms and Student's t test for independent samples was used for comparison of the averages of the values found by the Ocular Surface Disease Index (OSDI) questionnaire and the ocular tests between the patients of the groups. RESULTS: This study had evidenced a weak correlation between Ocular Surface Disease Index (OSDI) symptoms and ocular tests, which it indicates that not all the patients who presented exuberant symptoms, showed proportionally modified tests. The cornea sensitivity of the case group was reduced when compared with that of the control group. All the studied parameters in the case group presented significant differences (p<0.05) when compared with the control group. CONCLUSION: There was a weak correlation between Sjögren's syndrome patients' ocular symptoms and signals that indicate the severity of the illness. The variation of cornea sensitivity found in the Sjögren's syndrome patient group may be one of the responsible factors for this weak correlation. All the studied parameters were significantly modified in the Sjögren's syndrome patients group when compared with those found in the control group.
- ItemAcesso aberto (Open Access)Diagnóstico e tratamento da síndrome de Sjögren(Conselho Brasileiro de Oftalmologia, 2006-12-01) Felberg, Sergio [UNIFESP]; Dantas, Paulo Elias Correa; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)Sjögren's syndrome is a systemic inflammatory autoimmune disease with worldwide distribution, responsible for considerable impact on the patient's quality of life. The aim of this article is to describe its main symptoms, the currently used different diagnostic criteria and the available treatment for the syndrome.