Navegando por Palavras-chave "abdominal hernia"

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    Avaliação da cicatrização após implantação da tela de polipropileno/poliglecaprone na correção do defeito produzido na parede abdominal em ratos: efeito da administração do óleo de copaíba e andiroba
    (Universidade Federal de São Paulo (UNIFESP), 2013-01-30) Yasojima, Edson Yuzur [UNIFESP]; Lopes Filho, Gaspar de Jesus [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Objective: to evaluate the effects of copaiba and andiroba oil on the correction of abdominal defect treated with the use of polypropylene/polyglecaprone mesh in rats. Methods: a defect in the abdominal wall was created and corrected with polypropylene/polyglecaprone mesh in 60 rats. They were randomly divided into five groups: control, copaiba by oral administration (gavage), andiroba by gavage, copaiba oil dip in the mesh and andiroba oil dip in the mesh. Euthanasia was performed after 7, 14 and 21 post-operative days. The healing process was analyzed regarding the meshes and macroscopic and microscopic aspects. Results: all animals had abdominal adhesions, which were smaller in the copaiba (gavage) group (p<0.05). In microscopy, all animals had an acute inflammation stage and the inflammatory response was best characterized by foreign body-type granulomas around the mesh fragments, which was not found in the mesh fragments within the copaiba dip group. There was a greater area of necrosis and fibrosis in the copaiba and andiroba dip group compared to the control group (p<0.05). The copaiba and andiroba (gavage) groups had a greater quantity of collagen fibers compared to the control group. Conclusion: The copaiba and andiroba gavage groups showed a modulation of the inflammatory response, as evidenced by the reduced amount of adhesion without impair the healing process. Since the oils shortened the process of forming collagen fibers. However, when used by dip directly on the mesh, it had corrosive effects compromising the healing process of the abdominal wall.
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    Avaliação da cicatrização após implantação da tela de polipropileno/poliglecaprone na correção do defeito produzido na parede abdominal em ratos: efeito da administração do óleo de copaíba e andiroba
    (Universidade Federal de São Paulo (UNIFESP), 2013-01-30) Yasojima, Edson Yuzur [UNIFESP]; Lopes Filho, Gaspar de Jesus Lopes Filho [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Objective: to evaluate the effects of copaiba and andiroba oil on the correction of abdominal defect treated with the use of polypropylene/polyglecaprone mesh in rats. Methods: a defect in the abdominal wall was created and corrected with polypropylene/polyglecaprone mesh in 60 rats. They were randomly divided into five groups: control, copaiba by oral administration (gavage), andiroba by gavage, copaiba oil dip in the mesh and andiroba oil dip in the mesh. Euthanasia was performed after 7, 14 and 21 post-operative days. The healing process was analyzed regarding the meshes and macroscopic and microscopic aspects. Results: all animals had abdominal adhesions, which were smaller in the copaiba (gavage) group (p<0.05). In microscopy, all animals had an acute inflammation stage and the inflammatory response was best characterized by foreign body-type granulomas around the mesh fragments, which was not found in the mesh fragments within the copaiba dip group. There was a greater area of necrosis and fibrosis in the copaiba and andiroba dip group compared to the control group (p<0.05). The copaiba and andiroba (gavage) groups had a greater quantity of collagen fibers compared to the control group. Conclusion: The copaiba and andiroba gavage groups showed a modulation of the inflammatory response, as evidenced by the reduced amount of adhesion without impair the healing process. Since the oils shortened the process of forming collagen fibers. However, when used by dip directly on the mesh, it had corrosive effects compromising the healing process of the abdominal wall.