Navegando por Palavras-chave "demência vascular"

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    Depressão vascular no idoso: resposta ao tratamento antidepressivo associado a inibidor das colinesterases
    (Faculdade de Medicina da Universidade de São Paulo, 2007-01-01) Barcelos, Ricardo; Faria, Juliano [UNIFESP]; Grossi, Paulo; Aparício, Marco Antonio Moscoso; Bottino, Cássio M. C.; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP); Hospital Geral Santa Lúcia Centro de Terapia Intensiva
    CONTEXT: Among neuropsychiatric disorders caused by cerebrovascular factors, vascular depression is diagnosed in a small degree by general practitioners, causing morbid-mortality increase in elderly. CASE REPORT: That is a case of a 67 year-old-man with partial response after treatment with a Selective Serotonin Receptors Inhibitor, and severe autonomic adverse effects with other antidepressants. The addition of rivastigmine to citalopram resulted in a therapeutic success, with a reduction of 23 to 7 points on the Hamilton Depressive Scale (HAM-D). DISCUSSION: The result obtained brings new perspectives to the treatment of vascular depression, providing that randomized controlled trials with larger sample sizes confirm the positive effect of the addition of a cholinesterase inhibitor to antidepressants in the treatment of these patients.
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    Neuropsychological performance in patients with subcortical stroke
    (Academia Brasileira de Neurologia - ABNEURO, 2012-05-01) Andrade, Silviane Pinheiro Campos de [UNIFESP]; Brucki, Sônia Maria Dozzi; Bueno, Orlando Francisco Amodeo [UNIFESP]; Siqueira Neto, José Ibiapina; Universidade Federal de São Paulo (UNIFESP)
    Vascular cognitive impairment (VCI) is characterized by cognitive compromise predominantly of executive dysfunction. OBJECTIVES: To assess cognitive functions in VCI, focusing on executive functions, to observe functional losses in relation to activities of daily living (ADLs) and to detect early symptoms prior to the onset of dementia. METHODS: We evaluated healthy subjects matched for gender, education and age to patients with diagnosis of subcortical vascular disease who had a stroke classified into three groups: 1) vascular lesions and no impairment; 2) vascular cognitive impairment with no dementia (VCIND); 3) vascular dementia (VaD). RESULTS AND DISCUSSION: The performance on neuropsychological tests differed among groups, worsening with increased impairment level. The probable VaD group demonstrated impaired performance in memory, processing speed and verbal production, while the VCIND group showed attention deficits. CONCLUSION: Impairment in executive functions and difficulties in ADLs allow us to differentiate levels of impairment in groups of subcortical vascular disease.