Navegando por Palavras-chave "dermatomiosite juvenil"

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    Calcinose na infância, um desafio terapêutico
    (Sociedade Brasileira de Reumatologia, 2007-02-01) Castro, Tânia Caroline Monteiro de [UNIFESP]; Yamashita, Edson [UNIFESP]; Terreri, Maria Teresa Ramos Ascensão [UNIFESP]; Len, Claudio Arnaldo [UNIFESP]; Hilário, Maria Odete Esteves [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Calcinosis is a common and debilitating complication of dermatomyositis. It is a hallmark of the disease, occurring mainly in pediatric patients. Little is known about its pathophysiology, and there is no universally recognized treatment. This is a report of two children with juvenile dermatomyositis and severe calcinosis who showed improvement with the use of alendronate and diltiazen in one patient, and intravenous immunoglobulin in the other.
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    Dermatomiosite juvenil (DMJ) e comprometimento pulmonar grave: relato de caso
    (Sociedade Brasileira de Reumatologia, 2009-08-01) Silva, Érika Cristina Carneiro da [UNIFESP]; Bugni, Vanessa Monteiro [UNIFESP]; Terreri, Maria Teresa Ramos Ascensão [UNIFESP]; Castro, Márcia Helena de Oliveira [UNIFESP]; Ishigai, Márcia Marcelino de Souza [UNIFESP]; Hilário, Maria Odete Esteves [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Juvenile dermatomyositis (JDM) is an inflammatory, non-pustular disorder of skeletal muscles and skin. Other organs, such as the lungs, can be involved. Pulmonary complications are associated with high morbimortality rates and can develop in the acute phase of the disease. Due to its rarity, diagnosis difficulty and severity pulmonary involvement, we report the case of a 3-year-old girl with JDM and pulmonary involvement and evolution to death.
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    Dermatomiosite juvenil e linfoma de Hodgkin: uma rara associação
    (Sociedade Brasileira de Reumatologia, 2007-12-01) Cavalcanti, André [UNIFESP]; Terreri, Maria Teresa Ramos Ascensão [UNIFESP]; Sallum, Adriana Maluf Elias; Marie, Suely Kazue Nagahashi; Luisi, Flávio [UNIFESP]; Hilário, Maria Odete Esteves [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)
    Dermatomyositis (DM) in adults is frequently associated with cancer. In contrast, during childhood juvenile dermatomyositis (JDM) is predominantly idiopathic and its association with neoplasia is rare and based only in case reports. Although rare, the presence of neoplasia in JDM patients must always be suspected in face of atypical clinical manifestations and uncommon laboratorial findings. We describe and discuss a case of JDM and Hodgkin disease in an adolescent.
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    Miopatias inflamatórias na infância: correlações clínica e laboratorial com alterações capilaroscópicas
    (Sociedade Brasileira de Pediatria, 2006-02-01) Nascif, Ana Karina.Soares [UNIFESP]; Terreri, Maria Teresa Ramos Ascensão [UNIFESP]; Len, Claudio Arnaldo [UNIFESP]; Andrade, Luiz Eduardo Coelho [UNIFESP]; Hilário, Maria Odete Esteves [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE: Nailfold capillaroscopy is an important tool for the diagnosis and follow-up of patients with rheumatic diseases, in particular dermatomyositis and scleroderma. A relationship has been observed in adults between improved capillaroscopic findings and reduced disease activity. Our aim was to correlate disease activity (clinical and laboratory data) and nailfold capillaroscopy findings in 18 patients with inflammatory myopathies. METHODS: This prospective study included 13 juvenile dermatomyositis patients (Bohan and Peter criteria) (mean age of 8.8 years) and five patients with overlap syndrome (mean age of 15.7 years). We evaluated disease activity (skin abnormalities and muscle weakness, muscle enzymes and acute phase reactants) and its correlation with nailfold capillaroscopy findings (dilatation of isolated loops, dropout of surrounding vessels and giant capillary loops). We used a microscope with special light and magnification of 10 to 16X. RESULTS: Eighteen patients underwent a total of 26 capillaroscopic examinations, seven of them on two or more occasions (13 were performed during the active disease phase and 13 during remission). Twelve of the 13 examinations performed during the active phase exhibited scleroderma pattern and 8 of the 13 examinations performed during remission were normal. Therefore, in 20 of the 26 examinations clinical and laboratory data and nailfold capillaroscopy findings correlated (p = 0.01). CONCLUSIONS: Nailfold capillaroscopy is a non-invasive examination that offers satisfactory correlation with disease activity and could be a useful tool for the diagnosis and follow-up of inflammatory myopathies.