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- ItemAcesso aberto (Open Access)Dores recorrentes na infância e adolescência(Sociedade Brasileira de Pediatria, 2003-06-01) Puccini, Rosana Fiorini [UNIFESP]; Bresolin, Ana Maria B.; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP); Secretaria Municipal de Saúde de São PauloOBJECTIVE: to perform a bibliographic review of recurrent pain in children and adolescents, focusing on differential diagnosis and management of such patients. SOURCES OF DATA: search of Medline and Lilacs databases, covering the last four and ten years, respectively. Classical studies and texts related to the matter were also included. SUMMARY OF THE FINDINGS: studies carried out in different parts of the world demonstrate that the most frequent kinds of recurrent pain in children and adolescents are abdominal pain, headache, and limb pain. The occurrence of organic etiology is low, observed in 5% to 10% of the cases. Among the well defined organic etiology, no predominance is observed. The main advances regarding the pathophysiology of recurrent pain in its main localizations were analyzed. Guidelines for the diagnostic and therapeutic approach of the most common infantile diseases related to recurrent pain are presented. CONCLUSIONS: recurrent pain in children and adolescents is very common and determines significant demand on healthcare services. Defined etiology is only presented by 5% to 10% of patients. Anamnesis, physical examination and follow-up are extremely important instruments for dealing with such patients.
- ItemAcesso aberto (Open Access)Pain determinants of pain in autosomal dominant polycystic kidney disease(Sociedade Brasileira de Nefrologia, 2013-09-01) Nishiura, José Luiz [UNIFESP]; Eloi, Samara Rodrigues Moreira [UNIFESP]; Heilberg, Ita Pfeferman [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Pain is the most common symptom reported by ADPKD patients, afflicting approximately 60% of cases and may result from renal hemorrhage, calculi, urinary tract infections, cyst rupture, or due to stretching of the capsule or traction of the renal pedicle. We have recently investigated pain patterns in AD-PKD patients using a translated version of a pain questionnaire specific for AD-PKD population. The questionnaire revealed that 67% patients with ADPKD exhibited some type of pain. The findings of that study emphasized that pain appeared early in the course of ADPKD, when patients still exhibited preserved renal function. In the present study, a multivariate logistic regression analysis disclosed that renal volume (9-fold increased risk) and nephrolithiasis (4-fold increased risk) were the most important determinant factors for pain in ADPKD patients with preserved renal function, after adjustments for the presence of hypertension and duration of the disease.