Navegando por Palavras-chave "hospital infection"

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    Clinical and microbiological characterization of KPC-producing Klebsiella pneumoniae infections in Brazil
    (Brazilian Society of Infectious Diseases, 2011-02-01) Beirão, Elisa Maria; Furtado, Juvencio Jose Duailibe; Girardello, Raquel [UNIFESP]; Ferreira Filho, Heli; Gales, Ana Cristina [UNIFESP]; Hospital Heliópolis; Hospital Heliópolis Department of Infectious Diseases; Universidade Federal de São Paulo (UNIFESP); Hospital Heliópolis Microbiology Laboratory
    In 2008 isolates of KPC-producing Klebsiella pneumoniae (KPC-KPN) were detected for the first time at Hospital Heliópolis, São Paulo, Brazil. The aim of this study was to characterize the clinical and microbiological outcomes of infections caused by KPC-KPN. A historical cohort of patients from whom KPC-KPN strains were isolated was performed. Isolates were identified as resistant to ertapenem by automated broth microdilution system and screened as carbapenemase producers by the modified Hodge test. The beta-lactamase resistance gene blaKPC was detected by PCR. The genetic relatedness of isolates was determined by PFGE. The study provides early clinical experience in treating KPC-KPN infections in a Brazilian tertiary center.
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    Occurrence of IMP-1 in non-baumannii Acinetobacter clinical isolates from Brazil
    (Microbiology Soc, 2018) Cayô, Rodrigo [UNIFESP]; Streling, Ana Paula [UNIFESP]; Nodari, Carolina Silva [UNIFESP]; Matos, Adriana Pereira [UNIFESP]; Luz, Adryella de Paula [UNIFESP]; Dijkshoorn, Lenie; Pignatari, Antonio Carlos Campos [UNIFESP]; Gales, Ana Cristina [UNIFESP]
    The aim of this study was to characterize the presence of carbapenemase-encoding genes in distinct species of Acinetobacter spp. isolated from Brazilian hospitals. Five carbapenem-resistant Acinetobacter spp. isolates (two Acinetobacter pittii, two Acinetobacter bereziniae and one Acinetobacter junii) recovered from two distinct hospitals between 2000 and 2016 were included in this study. All of the isolates harboured bla(IMP-1), which was inserted into In86, a class 1 integron. Pulsed field gel eletrophoresis analysis showed that both A. pittii were identical, while the two A. berezinae isolates were considered to be clonally related. In this study, we demonstrated that mobile elements carrying carbapenemase-encoding genes such as In86 may persist for a long period, allowing their mobilization from A. baumannii to other Acinetobacter spp. that are usually susceptible to multiple antimicrobials.
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    Varicella zoster antibodies in healthcare workers from two neonatal units in São Paulo, Brazil - assessment of a staff varicella policy
    (W B Saunders Co Ltd, 2004-03-01) Dos Santos, Amelia Miyashiro [UNIFESP]; Ono, E.; Weckx, L. Y.; Coutinho, A. P.; Moraes-Pintoa, M. I. de; Universidade Federal de São Paulo (UNIFESP)
    Although frequently reported in the literature, a staff varicella policy is not standard in many hospitals even in developed countries. in the present study, we assessed varicella zoster immunity in staff from two neonatal units from hospitals in São Paulo, Brazil. Ninety-seven percent of all staff working in both units agreed to participate. A simple and cost-effective varicella policy was subsequently set up, based on costs and data from serology and a history of previous varicella infection. Our results confirm that a varicella vaccination programme can be implemented in a healthcare facility, even in developing countries. (C) 2003 the Hospital Infection Society. Published by Elsevier B.V. All rights reserved.