Navegando por Palavras-chave "imunoglobulina"
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- ItemAcesso aberto (Open Access)Calcinose na infância, um desafio terapêutico(Sociedade Brasileira de Reumatologia, 2007-02-01) Castro, Tânia Caroline Monteiro de [UNIFESP]; Yamashita, Edson [UNIFESP]; Terreri, Maria Teresa Ramos Ascensão [UNIFESP]; Len, Claudio Arnaldo [UNIFESP]; Hilário, Maria Odete Esteves [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Calcinosis is a common and debilitating complication of dermatomyositis. It is a hallmark of the disease, occurring mainly in pediatric patients. Little is known about its pathophysiology, and there is no universally recognized treatment. This is a report of two children with juvenile dermatomyositis and severe calcinosis who showed improvement with the use of alendronate and diltiazen in one patient, and intravenous immunoglobulin in the other.