Navegando por Palavras-chave "neurinoma do acústico"
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- ItemAcesso aberto (Open Access)Associação entre tamanho e potencial proliferativo em neurinomas do acústico(Academia Brasileira de Neurologia - ABNEURO, 2006-03-01) Tella, Oswaldo Inácio de [UNIFESP]; Stávale, João Norberto [UNIFESP]; Herculano, Marco Antonio [UNIFESP]; Paiva Neto, Manoel Antonio de [UNIFESP]; Onishi, Franz Jooji [UNIFESP]; Guimarães Filho, Francisco de Assis Vaz [UNIFESP]; Silva, Luciano Ricardo França e [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Hospital Professor Edmundo Vasconcelos; Faculdade de Medicina de JundiaíAcoustic neuromas are the most common tumors in the cerebellopontine angle. The molecular mechanisms involved in generation and growth of these tumors are not completly elucidated. Many radiological, clinic and imunohistochemystry data were correlated to tumor growth. We studied 11 acoustic neuromas surgically treated at Hospital São Paulo/UNIFESP and correlated clinical and radiological data with proliferative index (Ki-67). The size of the tumors were positively correlationated with proliferative index. No other correlation had statistic significativity.
- ItemAcesso aberto (Open Access)Schwannoma vestibular: involução tumoral espontânea(ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, 2007-12-01) Penido, Norma de Oliveira [UNIFESP]; Tangerina, Rodrigo P.; Kosugi, Eduardo Macoto [UNIFESP]; Abreu, Carlos Eduardo Cesário de; Vasco, Matheus Brandão; Universidade Federal de São Paulo (UNIFESP)The natural history of Vestibular Schwannomas (VS) is yet not totally known, but most of them have the tendency to slow growth, sometimes without any kind of symptoms during the individual s entire time. About 69% of diagnosed VS do not grow at all and 16% of these can even regress. Considering tumors that grow, about 70% have grown less than 2mm an year. Advanced radiological diagnosis, especially magnetic resonance imaging with gadolinium helps us diagnose small and less symptomatic tumors. Treatment of choice still is complete tumor resection. Surgical approaches have improved considerably and have helped preserve facial nerve function and hearing. Considering VS s natural history, there is a possibility for conservative treatment for these tumors, because their growth in the first year after diagnosis predicts tumor growth behavior in the next years. Surgery should be done in cases of tumor growth, patient s desire or symptoms worsening. Moreover, in terms of postoperative sequelae, there is no difference between patients who underwent surgery immediately after diagnosis and those who underwent initial conservative treatment for these tumors.