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- ItemAcesso aberto (Open Access)Anatomia microscópica do canal carótico e suas relações com a cóclea e a cavidade timpânica(ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, 2005-08-01) Penido, Norma de Oliveira [UNIFESP]; Borin, Andrei [UNIFESP]; Fukuda, Yotaka [UNIFESP]; Lion, Cristina Navarro Santos [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)The knowledge of the relations between the noble and vital structures of temporal bone is still a great challenge for the otologic surgeon. The microscopic anatomic studies of the temporal bone are one of the greatest help to prevent lesions during surgical intervention. AIM: To study the anatomic correlations between the carotid canal and the cochlea, and the occurrence of dehiscence of the carotid canal in the middle ear tympanic cavity. MANTERIAL AND METHODS: Microscopic study of 122 human temporal bones. RESULTS: The average distance between the carotid canal and the cochlea were: the shortest distance, 1.05mm; basal turn, 2.04mm; middle turn, 2.32mm; and apical turn, 5.70mm. The occurrence of dehiscence of the carotid canal inside the tympanic cavity was 35.2%. CONCLUSION: The small distances between the cochlea and carotid canal, and the high incidence of dehiscence in the tympanic cavity remind us that anatomical knowledge of the temporal bone is required for the best qualification of otologists.
- ItemAcesso aberto (Open Access)Corpo estranho de orelha, nariz e orofaringe: experiência de um hospital terciário(ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, 2006-04-01) Tiago, Romualdo Suzano Louzeiro [UNIFESP]; Salgado, Daniel Cauduro; Corrêa, Juliano Piotto; Pio, Márcio Ricardo Barros; Lambert, Ernani Edney; Universidade Federal de São Paulo (UNIFESP); Hospital do Servidor Público Municipal de São Paulo Serviço de OtorrinolaringologiaThe ocurrence of foreign bodies in otorhinolaryngology is reason of constant searches for emergency services. OBJECTIVE: To value the incidence of patients with foreign body, to analyze the clinical situation and the treatment in these cases. METHOD: The prospective study was realized in 81 patients with diagnosis of foreign body of nose, ear or oropharynx in the otorhinolaryngology service of the Hospital do Servidor Público Municipal de São Paulo between april/2003 and march/2005. RESULTS: 57 cases of foreign body of ear, 13 cases of nose and 11 of oropharynx. These patients, 51.85% were men and 48.15% were women. The age average was 23 years old. The average of the evolution time was 18.36 days, being that 38.27% these cases were taken care in less 24 hours of evolution. Inside the total of patients, 83.95% received initial attendance in the otorhinolaryngology clinic, and 16.05% came of another service after some previous removal attempt. The most common symptom of the foreign bodies cases of oropharynx it was odinofagia present in 90.91% of the cases; in the foreign bodies of nose, the unilateral rhinorrhea and cacosmia were present in 46.15 of the cases; in the foreign bodies of ear, 38.60% evolved without symptoms and 28.07 with hipoacusia. The most frequent foreign body of oropharynx it was the fish spine (54.55%); in the nose it was the paper (30.77%); and in the ear it was the cotton (31.58%). The complications resulting of the presence of foreign body or about the manipulation of these had been found in 13 cases (16.05%). CONCLUSION: Most cases of foreign body conditions, in which a non-specialist professional or a non-professional person previously handles its removal, have a bad evolution with emerging complications. Such outcomes strengthen the fact that an otorhinolaryngologist using the proper equipment must treat patients with foreign body.
- ItemAcesso aberto (Open Access)Estudo anatômico do osso temporal de um primata não-humano (Callithrix sp)(ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, 2008-06-01) Borin, Andrei [UNIFESP]; Covolan, Luciene [UNIFESP]; Mello, Luiz Eugenio Araujo de Moraes [UNIFESP]; Okada, Daniel Mochida [UNIFESP]; Cruz, Oswaldo Laércio Mendonça [UNIFESP]; Testa, Jose Ricardo Gurgel [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade Federal São Paulo Departamento OtorrinolaringologiaThe search for experimental (animal) models is essential to the development of clinical studies. AIM: To demonstrate, by means of micro dissection techniques, the anatomical structures of temporal bones from the primate Callithrix sp. STUDY DESIGN: Experimental. METHODS: Dissection of temporal bone structures of Callithrix sp and photographic documentation. RESULTS: We identified the main constituents of the temporal bone (external, medium and inner ear and facial nerve). CONCLUSION: The non-human primate Callithrix sp. is an adequate experimental model for the studies of temporal bone structures given its close anatomical similarities to that found in humans.
- ItemAcesso aberto (Open Access)Meningioma intracanalicular: diagnóstico por imunohistoquímica(ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, 2008-02-01) Borin, Andrei; Okada, Daniel Mochida; Cruz, Oswaldo Laércio Mendonça [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
- ItemSomente MetadadadosTerapia com células-tronco mesenquimais em modelo animal de ototoxicidade por canamicina(Universidade Federal de São Paulo (UNIFESP), 2014-10-31) Barros, Bruno Borges de Carvalho [UNIFESP]; Porcionatto, Marimelia Porcionatto [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Purpose: To evaluate the effect of MSC transplantation on hearing recovery in an animal model of ototoxicity. Methods: Experimental study with 20 adult mice C57 / BL6 submitted to kanamycin + furosemide hearing injury. After 24 hours of injury, mesenchymal stem cells (MSC) that express green fluorescent protein (GFP) were transplanted by transtympanic approach in 10 animals (Injury + MSC). The others animals received only DMEM (Injury). Auditory brainstem response (ABR) tresholds were obtained before injury and two weeks after treatment. Results: Hearing thresholds in group injury + MSC were statistically better than in the injury group. MSCs GFP + were identified by immunohistochemistry in sections of the inner ear. Conclusions: Transtympanic MSC therapy showed statistically better hearing thresholds, suggesting a protective effect against the ototoxic effects caused by AGs. We also noted the ability of these cells to cross the membrane of oval window under stimulus of ototoxic injury