Navegando por Palavras-chave "physiology"
Agora exibindo 1 - 6 de 6
Resultados por página
Opções de Ordenação
- ItemSomente MetadadadosDoppler echocardiography during pregnancy: Physiological and abnormal findings(Futura Publ Co, 1996-03-01) Campos, Orlando [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Despite continuous improvements in diagnostic cardiology techniques, echocardiography remains the cornerstone for noninvasive cardiovascular assessment of the pregnant woman with heart disease or suspected cardiac abnormality. Reversible physiological cardiac remodeling of pregnancy associated with changes in valve patency or transvalvular flow pattern, can be suitably assessed by the complementary use of quantitative pulsed- and continuous Doppler and qualitative color Doppler technology. These techniques are also useful for a better understanding of the pathophysiology of the hemodynamic consequences of fixed valve stenosis during pregnancy with respect to the labile nature of gradients resulting from variable loading conditions as occurs during pregnancy. Recent and specific areas of clinical use including cardiac output estimation, contrast echocardiography minimizing radioscopy during cardiac catheterization and transesophageal echocardiography for selection of patients with mitral stenosis suitable for percutaneous catheter valvotomy illustrate the large spectrum of capabilities of this versatile method during pregnancy.
- ItemAcesso aberto (Open Access)Força axial de língua em diferentes faixas etárias(Sociedade Brasileira de Fonoaudiologia, 2011-09-01) Motta, Andréa Rodrigues [UNIFESP]; César, Cibele Comini; Bommarito, Silvana [UNIFESP]; Chiari, Brasilia Maria [UNIFESP]; Universidade Federal de Minas Gerais; Universidade Federal de São Paulo (UNIFESP)PURPOSE: To analyze the maximum axial force, the mean axial force, the amount of energy accumulated by the tongue, and the time taken to reach the maximum axial force, in different age ranges. METHODS: The records of 92 individuals - students, staff and visitors at an university -, 29 (32.6%) men and 63 (67.4%) women, with ages between 14 and 53 years old, were analyzed. Subjects were divided into four age groups: 14 to 18 years, 19 to 23 years, 24 to 28 years, and 29 to 53 years. Each subject underwent clinical and instrumental assessment of the tongue. Instrumental assessment used FORLING. Data were statistically analyzed. RESULTS: Regarding the maximum force, the mean force and the tongue's accumulated energy, no differences were observed between groups. Regarding the time taken to reach the maximum force, the greatest values were obtained at the age range from 14 to 18 years (4.5 s), and the shortest values, at the age range from 19 to 23 years (3.1 s), with significant difference between the groups (p=0.001). CONCLUSION: Only the time taken to reach the tongue's maximum force is influenced by age range, indicating that teenagers are not able to reach the maximum lingual force as fast as young adults.
- ItemSomente MetadadadosPhenotypic characterization and ecological features of Coccidioides spp. from Northeast Brazil(Taylor & Francis Ltd, 2006-11-01) Cordeiro, R. A.; Brilhante, R. S. N.; Rocha, M. F. G.; Fechine, M. A. B.; Camara, L. M. C.; Camargo, Z. P.; Sidrim, J. J. C.; Univ Fed Ceara; Univ Estadual Ceara; Universidade Federal de São Paulo (UNIFESP)This study extends phenotypic and ecological knowledge of Coccidioides spp., by describing its recovery from soils of Ceara State (Northeast Brazil) and analyzing the in vitro features of the growth of its vegetative phase. Following a human coccidioidomycosis case, Coccidioides spp. strains were isolated from 3 of 14 soil samples collected in an armadillo's burrow. Mycological analysis showed colonies with glabrous, velvety or cottony texture and an increasing quantity of arthroconidia. the overall growth rates of the strains were slower in 8% NaCl medium, maximum growth rate was obtained at 30 degrees C, and their pH tolerance ranged from 4.0 to 11.0. Several carbohydrates and polyalcohol sources could be efficiently metabolized by Coccidioides spp. strains in the mycelial form. Total absence of growth was observed in media supplemented with either L-aspartic acid or L-histidine. Whereas intense growth was found when strains were incubated with any other aminoacid sources studied. Coccidioides spp. strains did not grow in the presence of Tween 60 and Tween 80, but exhibited intense growth in Tween 20. Nicotinic acid and the toxic compounds caffeic acid and phenol could not be metabolized by any strain. All of the strains were positive for urease production and displayed intense growth in media containing cycloheximide concentrations ranging from 0.01 and 0.05%, but did not grow at 0.1 and 0.2%. the present findings confirm the importance of armadillos burrows in the ecology of Coccidioides spp. in Northeast Brazil and indicate that the fungus is a very physiologically versatile organism.
- ItemSomente MetadadadosPorphyrin Distribution After Topical Aminolevulinic Acid in a Novel Porcine Model of Sebaceous Skin(Wiley-Blackwell, 2009-02-01) Sakamoto, Fernanda Hidemi [UNIFESP]; Tannous, Zeina; Doukas, Apostolos G.; Farinelli, William A.; Smith, Nicholas A.; Zurakowski, David; Anderson, R. Rox; Harvard Univ; Universidade Federal de São Paulo (UNIFESP)Background and Objective: Aminolevulinic acid photodynamic therapy (ALA-PDT) depends on drug metabolism into porphyrins. Clinically, ALA-PDT has been used with a wide range of protocols for treating both epidermal and dermal targets, despite limited understanding of porphyrin biodistribution over time. We studied porphyrin accumulation after topical application of ALA in vivo, and also describe the porcine ear as a new animal model to study adnexal glands.Study Design/Materials and Methods: the microanatomy of anterior ear skin of swine was measured. Topical 20% ALA in water/ethanol was applied under occlusion. Biopsies taken after 5, 10, 15, and then every 15 minutes for a total of 3 hours were examined by fluorescence microscopy of frozen sections to assess accumulation and distribution of porphyrins.Results: Porphyrin fluorescence of digital photomicrograph images was not visually apparent until 3045 minutes after application, although quantitative pixel analysis showed a statistically significant increase in epidermal fluorescence only 15 minutes after ALA application. From 30 to 120 minutes, epidermis, hair follicles (HF), and sebaceous glands (SG) became progressively more fluorescent. Eccrine gland fluorescence began to be detected after 30 minutes; SG showed fluorescence starting at 45-75 minutes. Fluorescence in all sites reached maximum intensity from 75 to 180 minutes of incubation. There was a trend for HF and SG to express stronger fluorescence compared with epidermis and eccrine glands.Conclusion: Anterior pig ear skin is microanatomically similar to human sebaceous skin. the time-dependent accumulation of porphyrins in pilosebaceous units and eccrine glands in this model suggests other routes of uptake of topical ALA in addition to the trans-epidermal route. Apparently, time interval between ALA application and light exposure could be optimized for different uses of ALA-PDT. Lasers Surg. Med. 41:154-160, 2009. (C) 2009 Wiley-Liss, Inc.
- ItemSomente MetadadadosUrinary pH in panic disorder(Elsevier B.V., 2005-04-15) Lacerda, ALT; Caetano, D.; Keshavan, M. S.; Universidade Federal de São Paulo (UNIFESP); Universidade Estadual de Campinas (UNICAMP); Wayne State UnivUrinary pH was evaluated in panic disorder (PD) patients compared with both psychiatric and healthy control subjects. Fourteen PD patients, eight major depressive disorder (MDD) patients, and 14 healthy control (HC) subjects were examined. All patients were drug-free and met DSM-IV diagnostic criteria. the PD patients had lower urinary pH and higher levels of anxiety than both MDD and HC subjects. Additionally, urinary p inversely correlated with anxiety levels. Although preliminary, these findings suggest that PD patients have lower urinary pH than MDD and HC subjects. Future studies that simultaneously examine both urinary and blood pH in larger numbers of PD patients and patients with other anxiety disorders, before and after treatment, need to be conducted. © 2005 Elsevier Ireland Ltd. All rights reserved.
- ItemSomente MetadadadosWorkshop report: "Using Social Media and Smartphone Applications in Practical Lessons to Enhance Student Learning" in Buzios, Brazil (August 6-8, 2017)(Amer Physiological Soc, 2018) Lellis-Santos, Camilo [UNIFESP]; Halpin, Patricia A. [UNIFESP]Cost-effective student engagement poses a challenge for instructors, especially those who may not be familiar with new technologies and mobile devices. In this workshop, participants, experienced and discussed two ways of using smartphones in physiology classes: to engage in an online learning environment for discussions, and to make physiological measurements. Participants signed up for individual Twitter accounts and learned how to tweet, retweet. message, use a URL shortener, and use hashtags. They then went on to locate articles on an assigned topic from the Twitter accounts of credible science sources (American Journal of Physiology, The Scientist, CDC.gov , WHO.int) and applied their Twitter skills to discuss the science topic of current interest. Additionally, participants shared their knowledge about the use of smartphones as a tool for teaching