Navegando por Palavras-chave "somatosensory evoked potential"

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    Componente p18 do potencial evocado somatossensitivo por estimulação do nervo mediano
    (Universidade Federal de São Paulo (UNIFESP), 2014-12-31) Giuliano, Lydia Maria Pereira [UNIFESP]; Manzano, Gilberto Mastrocola Manzano [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Objective: To investigate the P18 component in the posterior to anterior neck montage after median nerve stimulation. Methods: Somatosensory evoked potentials, through electrical wrist stimulation, were collected. In 12 subjects, the presence of the P18 component was evaluated in the posterior to anterior neck montage. In 10 subjects, the effects of stimulation vibration of the hand were evaluated. In five subjects, responses after double-pulse stimulation (ISI 20 ms) were evaluated. Results: The component P18 was identified in all subjects. Vibration reduced the amplitude of all components except the P18 and N18. Double-pulse stimulation reduced the amplitude of the P18 and the N18 components without significantly changing the amplitude of the others components. Conclusions: The posterior to anterior neck montage allows for recording the P18 component. The amplitude reduction of all components during vibration, exceptN18 and P18, is interpreted as reflecting inhibitory activities at the cuneiform nucleus and the segmental dorsal horn of the spinal cord, respectively. The reduction in the P18 component after double-pulse stimulation is compatible with previous observations on the positive component of cord dorsum potentials. Significance: Studying this component may add to the knowledge of function of the spinal cord in humans.
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    Median nerve SEP after a high medullary lesion: preserved N18 and absent P14 components (case report)
    (Academia Brasileira de Neurologia - ABNEURO, 1999-06-01) Manzano, Gilberto Mastrocola [UNIFESP]; Schultz, Rodrigo Rizek [UNIFESP]; Barsottini, Orlando Graziani Povoas [UNIFESP]; Zukerman, Eliova [UNIFESP]; Nóbrega, João Antonio Maciel [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Median nerve SEPs recorded from a patient with a high medullary lesion are described. The lesion involved the anteromedial and anterolateral right upper third of the medulla, as documented by MRI. Forty one days after the lesion, left median nerve SEP showed preserved N18 and absent P14 and N20 components; stimulation of the right median nerve evoked normal responses. These findings agree with the proposition that low medullary levels are involved in the generation of the N18 component of the median nerve SEP.
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    Relação entre tempo de condução motora central e tempo de condução sensitiva central na avaliação do neurônio motor superior
    (Universidade Federal de São Paulo (UNIFESP), 2015-01-28) Kawagoe, Kleber Edson [UNIFESP]; Manzano, Gilberto Mastrocola Manzano [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Introduction: To reduce the time to diagnosis and to find a biomarker are current concerns in Amyotrophic Lateral Sclerosis (ALS) having as main purposes possible early treatments and evaluation of their efficacy. However, there is a paucity of tests reliable for this purpose, mainly for the neurophysiological study of upper motor neuron (UMN). Objective: to evaluate the ratio between the Central Motor Conduction Time (CMCT) and Central Sensory Conduction Time (CSCT) in Motor Neuron Diseases (MND). Methods: CMCT and CSCT (peak ? pCSCT and onset - oCSCT) were measured from the median and ulnar nerves bilaterally, in 21 healthy volunteers (controls) and in 18 patients with acquired MND, and the ratio (CMCT/CSCT) was calculated. UMN involvement was evaluated according to deep tendon reflexes and MND clinical type. Results: only CMCT/oCSCT ratio (oR) showed significant difference in both median nerves, when comparing controls and patients with brisk reflexes ? right median nerve (p = 0.0053) and left median nerve (p = 0.0083). Conclusions: The ratio CMCT/CSCT between onset was able to detect involvement in different types of MND. New studies with this ratio should be evaluated in relation to ALS progression in UMN.