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- ItemAcesso aberto (Open Access)Giardia lamblia e alergia respiratória: estudo em uma amostra de crianças de área urbana com frequência elevada da protozoose(Sociedade Brasileira de Pediatria, 2012-06-01) Souza, Valdênia M. O.; Sales, Iana R. F.; Peixoto, Décio Medeiros [UNIFESP]; Costa, Vláudia M. Assis; Rizzo, José A.; Silva, Almerinda R.; Camilo, Roberta Faria [UNIFESP]; Pierotti, Felipe Faria; Solé, Dirceu [UNIFESP]; Sarinho, Emanuel S. C.; Universidade Federal de Pernambuco Laboratório de Imunopatologia Keizo Asami; UFPE Laboratório de Imunopatologia Keizo Asami; UFPE Hospital das Cínicas Imunologia; UFPE Hospital das Clínicas Imunologia; UFPE Hospital das Clínicas; Universidade Federal de São Paulo (UNIFESP); UFPE; UFPE Programa de Pós-graduação em Ciências da SaúdeOBJECTIVES: There is a high incidence of intestinal parasite infection in urban areas in the Northeast of Brazil. Giardia lamblia infections have been associated with increased prevalence of cutaneous allergies and gastrointestinal disorders. However, little is known about the relationship between giardiasis and allergic diseases of the airways. The present study aimed to investigate the possible association between respiratory allergic diseases and infections by G. lamblia in children from urban areas. METHODS: This study recruited 110 patients of both sexes aged 5-15 years. Patients were administered a questionnaire evaluating clinical symptoms and were given skin tests, parasite tests and serum tests. RESULTS: A high incidence of G. lamblia was observed (45%, 50/110). Infections by this protozoan were not associated with increased risk of respiratory allergy (p = 0.075), high total IgE levels (p = 0.701), positive specific IgE tests (p = 0.250), or positive skin tests for a range of environmental allergens (p = 0.239). CONCLUSION: This study demonstrated that symptoms of asthma, skin allergy and serum markers were not associated with G. lamblia infections in this sample of children from urban areas.