Navegando por Palavras-chave "vacinas contra papillomavirus"

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    Efeito da vacina contra papilomavírus humano (tipos 6, 11, 16 e 18) no tratamento de crianças com papilomatose respiratória recorrente
    (Universidade Federal de São Paulo (UNIFESP), 2015-12-16) Hermann, Juliana Sato [UNIFESP]; Pignatari, Shirley Shizue Nagata Pignatari [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Purpose: To evaluate whether the tetravalent vaccine against human papilomavírus (HPV) (types 6, 11, 16 and 18), when administered in a group of patients with juvenile-onset recurrent respiratory papillomatosis (RRP), influences the clinical course of the disease. Method: Uncontrolled intervention study of patients with juvenile-onset RRP of the Clinic of Pediatric Otorhinolaryngology, Federal University of São Paulo, where nine patients aged between 9-17 years received three doses of prophylactic quadrivalent vaccine against HVP (Gardasil®) and were followed for one year. The staging of disease, the intervals between relapses, the intervals between surgeries and their number during the year prior to vaccination and the first year of follow-up after vaccination were compared. Results: Eight patients had disease due to HPV-6 and one per HPV-11. There was no statistically significant change between the previous and subsequent years of vaccination in relation to clinical score (p = 0,083), anatomical score (p = 0,257), interval between relapses (p = 0,062), interval between surgery (p = 0,357) and the number of surgeries (p = 0,180). All patients had relapsed following vaccination. Conclusion: Vaccination with Gardasil® did not affect the clinical course of patients with juvenile-onset RRP during the study period.
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    Tratamento cirurgico e terapias adjuvantes na papilomatose respiratoria
    (Associação Brasileira de Otorrinolaringologia e Cirurgia Cervicofacial, 2013-09-01) Avelino, Melissa Ameloti Gomes [UNIFESP]; Zaiden, Tallyta Campos Domingues Teixeira; Gomes, Raquel Oliveira; Universidade Federal de São Paulo (UNIFESP); Universidade Federal de Goias; PUC - GO; Pontificia Universidade Catolica de Goias curso de Medicina
    Recurrent respiratory papillomatosis or recurrent laryngeal papillomatosis is a disease of the larynx caused by human papilloma virus, characterized by verrucous epithelial lesions and usually recurring. In the literature there are several types of treatment, such as surgery to cold, laser and/or use of microdebrider, as of adjuvant therapies; all possible to decrease the permanent sequelae of the disease.OBJECTIVE:To review the literature regarding this disease with emphasis on surgical techniques and adjuvant therapies used today.METHOD:We used the literature review, through surveys based electronic data in the public domain, to search for articles between 1992-2012, using keywords: papilloma, human pappiloma virus infection, larynx, therapeutic, papilloma virus vaccine.RESULTS:We surveyed 357 articles, of which 49 were used as the basis for this review. Scientific studies indicate a reduction of relapse in most adjuvant therapeutic presented. However, the survey showed different methodologies and samples, which did not allow to compare the types of treatment and adjuvant therapies.CONCLUSION:The choice of surgical technique varies among studies, but there is a trend to use the microdebrider. The newer adjuvant therapies, such as cidofovir, quadrivalent vaccine against human papilloma virus and bevacizumab, require further studies.