Comparison of cytogenetics with FISH in 40 myelodysplastic syndrome patients
| dc.contributor.author | Romeo, M. | |
| dc.contributor.author | Chauffaille, M. D. | |
| dc.contributor.author | Silva, MRR | |
| dc.contributor.author | Bahia, DMM | |
| dc.contributor.author | Kerbauy, J. | |
| dc.contributor.institution | Universidade Federal de São Paulo (UNIFESP) | |
| dc.date.accessioned | 2016-01-24T12:33:34Z | |
| dc.date.available | 2016-01-24T12:33:34Z | |
| dc.date.issued | 2002-11-01 | |
| dc.description.abstract | Karyotyping is important for diagnosis and prognosis of myelodysplastic syndrome (MDS). Using fluorescence in situ hybridization (FISH) either mitotic or interphase cells can be analyzed and a higher number of cells can be screened. This study evaluated the effectiveness of FISH in detecting the most common chromosomal abnormalities [-5/del 5q/-7/+8/del 11q23 and -Y] in 40 patients with MDS. Karyotype detected abnormalities in 35.2% of the patients and FISH in 35%, while some abnormalities remained undetected by each approach but the association of both methods increased the detection rate up to 40%. (C) 2002 Elsevier B.V. All rights reserved. | en |
| dc.description.affiliation | UNIFESP, EPM, Disciplina Hematol & Hemoterapia, BR-04023900 São Paulo, SP, Brazil | |
| dc.description.affiliationUnifesp | UNIFESP, EPM, Disciplina Hematol & Hemoterapia, BR-04023900 São Paulo, SP, Brazil | |
| dc.description.source | Web of Science | |
| dc.format.extent | 993-996 | |
| dc.identifier | http://dx.doi.org/10.1016/S0145-2126(02)00047-4 | |
| dc.identifier.citation | Leukemia Research. Oxford: Pergamon-Elsevier B.V., v. 26, n. 11, p. 993-996, 2002. | |
| dc.identifier.doi | 10.1016/S0145-2126(02)00047-4 | |
| dc.identifier.issn | 0145-2126 | |
| dc.identifier.uri | http://repositorio.unifesp.br/handle/11600/27022 | |
| dc.identifier.wos | WOS:000179134700007 | |
| dc.language.iso | eng | |
| dc.publisher | Elsevier B.V. | |
| dc.relation.ispartof | Leukemia Research | |
| dc.rights | info:eu-repo/semantics/restrictedAccess | |
| dc.rights.license | http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy | |
| dc.subject | FISH | en |
| dc.subject | myelodysplastic syndrome | en |
| dc.subject | karyotype | en |
| dc.title | Comparison of cytogenetics with FISH in 40 myelodysplastic syndrome patients | en |
| dc.type | info:eu-repo/semantics/article |