Möbius Syndrome: Misoprostol Use and Speech and Language Characteristics

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dc.contributor.authorGuedes, Zelita Caldeira Ferreira
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2015-06-14T13:47:16Z
dc.date.available2015-06-14T13:47:16Z
dc.date.issued2014-09-01
dc.description.abstractIntroduction Möbius syndrome (MS; VI and VII palsy) is a rare disease that in Brazil has a great frequency because of the use of misoprostol during pregnancy. Objective Verify if the speech and language performance of children with MS whose mothers reported use of misoprostol (Cytotec, Pfizer, Connecticut, USA) are different from the performance of children of mothers who did not report use. Methods The stomatognathic system beyond receptive and expressive language and speech was evaluated in children with MS, and their mothers were questioned whether they used misoprostol during the pregnancy. Results During the interview, 61.11% of mothers reported that they took misoprostol during the pregnancy. Most of the subjects (83.3%) whose mothers took misoprostol presented bilateral palsy beyond bad mobility of the tongue (90.9%) and speech disorders (63.6%). Conclusion The number of mothers who took misoprostol without knowing the risk for MS was great. The lack of facial expressions and speech disorders were common characteristics of the individuals with MS, whether the mothers took misoprostol during the pregnancy or not.en
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Department of Speech and Language
dc.description.affiliationUnifespUNIFESP, EPM, Department of Speech and Language
dc.description.sourceSciELO
dc.format.extent239-243
dc.identifierhttp://dx.doi.org/10.1055/s-0033-1363466
dc.identifier.citationInternational Archives of Otorhinolaryngology. Fundação Otorrinolaringologia, v. 18, n. 3, p. 239-243, 2014.
dc.identifier.doi10.1055/s-0033-1363466
dc.identifier.fileS1809-48642014000300239.pdf
dc.identifier.issn1809-4864
dc.identifier.scieloS1809-48642014000300239
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/8566
dc.language.isoeng
dc.publisherFundação Otorrinolaringologia
dc.relation.ispartofInternational Archives of Otorhinolaryngology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectmisoprostolen
dc.subjectspeech disordersen
dc.subjectrehabilitation of speech and language disordersen
dc.titleMöbius Syndrome: Misoprostol Use and Speech and Language Characteristicsen
dc.typeinfo:eu-repo/semantics/article
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