Auras in temporal lobe epilepsy with hippocampal sclerosis: Relation to seizure focus laterality and post surgical outcome

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dc.contributor.authorFerrari-Marinho, Taissa [UNIFESP]
dc.contributor.authorCaboclo, Luís Otávio Sales Ferreira [UNIFESP]
dc.contributor.authorMarinho, Murilo Martinez [UNIFESP]
dc.contributor.authorCenteno, Ricardo Silva [UNIFESP]
dc.contributor.authorNeves, Rafael Scarpa da Costa [UNIFESP]
dc.contributor.authorSantana, Maria Teresa Castilho Garcia de [UNIFESP]
dc.contributor.authorBritto, Fernanda dos Santos [UNIFESP]
dc.contributor.authorCarrete Junior, Henrique [UNIFESP]
dc.contributor.authorYacubian, Elza Márcia Targas [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:27:08Z
dc.date.available2016-01-24T14:27:08Z
dc.date.issued2012-05-01
dc.description.abstractWe examined the relationship between presence and frequency of different types of auras and side of lesion and post surgical outcomes in 205 patients with medically intractable mesial temporal lobe epilepsy (MTLE) with unilateral hippocampal sclerosis (HS). With respect to the number of auras, multiple auras were not associated with side of lesion (p=0.551). the side of HS was not associated with the type of auras reported. One hundred fifty-seven patients were operated. the occurrence of multiple auras was not associated with post-surgical outcome (p=0.740). the presence of extratemporal auras was significantly higher in patients with poor outcome. in conclusion, this study suggests that the presence of extratemporal auras in patients with MTLE-HS possibly reflects extratemporal epileptogenicity in these patients, who otherwise showed features suggestive of TLE. Therefore, TLE-HS patients undergoing pre-surgical evaluation and presenting clinical symptoms suggestive of extratemporal involvement should bemore extensively evaluated to avoid incomplete resection of the epileptogenic zone. (C) 2012 Elsevier Inc. All rights reserved.en
dc.description.affiliationUniversidade Federal de São Paulo, Dept Neurol & Neurocirurgia, BR-04024002 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Diagnost Imagem, BR-04024002 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Neurol & Neurocirurgia, BR-04024002 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Diagnost Imagem, BR-04024002 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent120-125
dc.identifierhttp://dx.doi.org/10.1016/j.yebeh.2012.03.008
dc.identifier.citationEpilepsy & Behavior. San Diego: Academic Press Inc Elsevier Science, v. 24, n. 1, p. 120-125, 2012.
dc.identifier.doi10.1016/j.yebeh.2012.03.008
dc.identifier.fileWOS000303814100021.pdf
dc.identifier.issn1525-5050
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/34815
dc.identifier.wosWOS:000303814100021
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofEpilepsy & Behavior
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectTemporal lobe epilepsyen
dc.subjectHippocampal sclerosisen
dc.subjectAurasen
dc.subjectExtratemporal aurasen
dc.subjectPost surgical outcomeen
dc.titleAuras in temporal lobe epilepsy with hippocampal sclerosis: Relation to seizure focus laterality and post surgical outcomeen
dc.typeinfo:eu-repo/semantics/article
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