Safety of video-EEG monitoring and surgical outcome in patients with mesial temporal sclerosis and psychosis of epilepsy

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dc.contributor.authorConceição, Priscila Oliveira da [UNIFESP]
dc.contributor.authorAraujo Filho, Gerardo Maria de [UNIFESP]
dc.contributor.authorMazetto, Lenon [UNIFESP]
dc.contributor.authorAlonso, Neide Barreira [UNIFESP]
dc.contributor.authorYacubian, Elza Márcia Targas [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:27:44Z
dc.date.available2016-01-24T14:27:44Z
dc.date.issued2012-10-01
dc.description.abstractPurpose: Cortico-amygdalohippocampectomy (CAH) has become an important treatment option for patients with refractory temporal lobe epilepsy and mesial temporal sclerosis (TLE-MTS); it has resulted in a 60-70% seizure remission rate and significant quality of life (QOL) improvements. Video-electroencephalography (VEEG) monitoring has been widely used in epilepsy centers for pre-surgical evaluation. A major concern in epilepsy surgery is whether to consider CAH treatment in patients with psychosis of epilepsy (POE). This study analyzed the safety and adverse events (AEs) of VEEG monitoring and the post-surgical outcomes of patients with refractory TLE-MTS and POE who underwent CAH.Method: Clinical, sociodemographic and VEEG data from 18 patients with TLE-MTS and POE were analyzed. Psychiatric evaluations were performed using DSM-IV and ILAE criteria. the seizure outcome was evaluated using Engel's criteria.Results: Two patients (11.2%) presented AEs that did not result in increased lengths of hospitalization. of the 10 patients (55.5%) who underwent CAH, 6 (60%) became free of disabling seizures (Engel I). the psychiatric and QOL evaluations revealed improvements of psychotic symptoms (p = 0.01) and in Physical Health (p = 0.01) following surgery.Conclusion: These data reinforce that VEEG monitoring is a safe method to evaluate patients with refractory TLE-MTS and POE in epilepsy centers. (C) 2012 British Epilepsy Association. Published by Elsevier B.V. All rights reserved.en
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Neurol & Neurosurg, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, Dept Psychiat, LiNC, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Neurol & Neurosurg, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, Dept Psychiat, LiNC, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent583-587
dc.identifierhttp://dx.doi.org/10.1016/j.seizure.2012.06.002
dc.identifier.citationSeizure-european Journal of Epilepsy. London: W B Saunders Co Ltd, v. 21, n. 8, p. 583-587, 2012.
dc.identifier.doi10.1016/j.seizure.2012.06.002
dc.identifier.fileWOS000308628500005.pdf
dc.identifier.issn1059-1311
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/35302
dc.identifier.wosWOS:000308628500005
dc.language.isoeng
dc.publisherW B Saunders Co Ltd
dc.relation.ispartofSeizure-european Journal of Epilepsy
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMesial temporal sclerosisen
dc.subjectPsychoses of epilepsyen
dc.subjectVideo-EEG monitoringen
dc.subjectSurgical outcomeen
dc.titleSafety of video-EEG monitoring and surgical outcome in patients with mesial temporal sclerosis and psychosis of epilepsyen
dc.typeinfo:eu-repo/semantics/article
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