Surgical Treatment Alone of Cerebral Aspergillosis in Immunocompetent Patient

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dc.contributor.authorBeraldo, Daniel [UNIFESP]
dc.contributor.authorGuerra, Ramon
dc.contributor.authorAlvarenga, Vinicius
dc.contributor.authorCrepaldi, Leticia
dc.date.accessioned2019-07-22T15:46:44Z
dc.date.available2019-07-22T15:46:44Z
dc.date.issued2016
dc.description.abstractAspergillosis is a disease that predominantly affects immunocompromised patients. The incidence in immunocompetents is rare, and manifestation is generally pulmonary. Few reports in the literature refer to isolated cerebral aspergillosis in individuals with no chronic comorbidities. We describe a case of a 59-year-old rural worker without previous pathologies who had a partial convulsive crisis in a subtle form, with self-limiting and non recurrent secondary generalization. Diagnostic investigation demonstrated a sub cortical tumorlike lesion in the right precentral gyrus by nuclear magnetic resonance that allowed en bloc microsurgical resection, with histopathologic findings indicating cerebral aspergillosis. Because of the delay in obtaining the result of the biopsy due to technical difficulties with analysis, the diagnosis was delayed. The patient was clinically stable, with imaging without modifications and with negative serologic tests, so it was decided to follow the patient without antifungal therapy, which was successful. This was a case of isolated cerebral aspergillosis in an immunocompetent individual who was successfully treated by complete resection of the lesion alone, without combined antifungal therapy.en
dc.description.affiliationUniv Fed Sao Paulo, Dept Nephrol, Botucatu St,N740 Vila Clementino, BR-04023062 Sao Paulo, SP, Brazil
dc.description.affiliationHosp Renascentista, Dept Internal Med, Pouso Alegre, MG, Brazil
dc.description.affiliationHosp Clin Samuel Libanio, Dept Neurosurg, Pouso Alegre, MG, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Nephrol, Botucatu St,N740 Vila Clementino, BR-04023062 Sao Paulo, SP, Brazil
dc.description.sourceWeb of Science
dc.format.extent452-456
dc.identifierhttp://dx.doi.org/10.1055/s-0035-1558415
dc.identifier.citationJournal Of Neurological Surgery Part A-Central European Neurosurgery. New York, v. 77, n. 5, p. 452-456, 2016.
dc.identifier.doi10.1055/s-0035-1558415
dc.identifier.issn2193-6315
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/51049
dc.identifier.wosWOS:000388993200013
dc.language.isoeng
dc.publisherThieme Medical Publ Inc
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectaspergillosisen
dc.subjectcentral nervous systemen
dc.subjectseizuresen
dc.titleSurgical Treatment Alone of Cerebral Aspergillosis in Immunocompetent Patienten
dc.typeinfo:eu-repo/semantics/article
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