Does the choice of surgical approach to insert an intratumoral catheter influence the results of intratumoral cystic treatment?

Página do item simplificado
dc.contributor.authorZanon, Nelci
dc.contributor.authorCavalheiro, Sergio
dc.contributor.authorSilva, Marcia C. da
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T13:51:31Z
dc.date.available2016-01-24T13:51:31Z
dc.date.issued2008-07-01
dc.description.abstractBackground: in the literature, only a few articles are related to the surgical approach for insertion of an intratumoral catheter. No one has evaluated the complications related to the different surgical techniques for the treatment of pediatric cystic craniopharyngiomas.Methods: A cooperative, multicenter (France and Brazil) study was carried out and included 50 patients (aged between 9 months and 21 years) diagnosed as having cystic craniopharyngioma treated between 1990 and 2000. Forty-nine children were available for the final analysis. the patients were divided into 3 groups: group I, 24 children who underwent a craniotomy and catheter placement under direct vision using a surgical microscope; group II, 14 children who were submitted to a stereotactic approach for the placement of the intratumoral catheter; and group III, 11 children whose catheters were placed by a freehand approach through a burr hole.Results: Eight children (16.3%) presented complications related to the placement of the catheter, namely, misplacement or leakage. the rate of the complications did not appear to be related to one specific modality of the catheter insertion.Conclusion: Intracystic antiblastic drug injection is one available option in the treatment of cystic craniopharyngiomas. Because of the toxic effect of these drugs on the brain, determination of the exact placement to avoid leakage is mandatory for correct treatment. However, the results of the present study appear to indicate an excessively high incidence of complications whichever technique is used. (C) 2008 Published by Elsevier Inc.en
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Div Neurosurg, Post Grad Studies, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Dept Neurol, Post Grad Studies, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Escola Paulista Med, Dept Neurosurg, Post Grad Studies, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Div Neurosurg, Post Grad Studies, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Dept Neurol, Post Grad Studies, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Escola Paulista Med, Dept Neurosurg, Post Grad Studies, São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent66-69
dc.identifierhttp://dx.doi.org/10.1016/j.surneu.2007.05.048
dc.identifier.citationSurgical Neurology. New York: Elsevier B.V., v. 70, n. 1, p. 66-69, 2008.
dc.identifier.doi10.1016/j.surneu.2007.05.048
dc.identifier.issn0090-3019
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/30775
dc.identifier.wosWOS:000257731900012
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofSurgical Neurology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.rights.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.subjectintratumoral catheteren
dc.subjectsurgical approachen
dc.subjectcystic craniopharyngiomaen
dc.subjectbleomycinen
dc.subjectRickhamen
dc.subjectOmmaya reservoiren
dc.titleDoes the choice of surgical approach to insert an intratumoral catheter influence the results of intratumoral cystic treatment?en
dc.typeinfo:eu-repo/semantics/article
Arquivos
Coleções
EPM - Artigos