The Effect of Citalopram Versus a Placebo on Central Auditory Processing in the Elderly

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dc.citation.issue9
dc.citation.volume38
dc.contributor.authorPolanski, Jose Fernando [UNIFESP]
dc.contributor.authorSoares, Alexandra Dezani [UNIFESP]
dc.contributor.authorPereira, Liliane Desgualdo [UNIFESP]
dc.contributor.authorde Mendonca Cruz, Oswaldo Laercio [UNIFESP]
dc.coveragePhiladelphia
dc.date.accessioned2020-08-04T13:39:55Z
dc.date.available2020-08-04T13:39:55Z
dc.date.issued2017
dc.description.abstractObjective: Evaluate the effects of therapy with citalopram on the central auditory processing in the elderly measured by central auditory tests. Study Design: Prospective, randomized, double-blind, placebo-controlled study. Setting: Tertiary referral center. Patients: Thirty-nine patients older than 60 years with normal hearing thresholds or symmetrical sensorineural hearing loss up to 70 dBHL, word-recognition score equal to or better than 70%, and diagnosed with central auditory processing disorders completed the study. They underwent the mini-mental state examination, as a way to screen those with the possibility of dementiaen
dc.description.abstractthey also underwent the Beck depression inventory, for screening individuals with depression. Intervention: Citalopram 20 mg/d or placebo for 6 months. Main Outcome Measure: The central auditory tests were applied to the selection of individuals with auditory processing disorders and repeated after 6 months' treatment. The tests were sound localization, speech in noise, dichotic digits test, pitch pattern sequence, duration pattern test, and gaps-innoise. Results: Comparisons of central auditory tests pre- and posttreatment in groups showed: sound localization (p = 0.022), pitch pattern sequence humming (p = 0.110), pitch pattern sequence nomination (p = 0.355), duration pattern test humming (p = 0.801), duration pattern test nomination (p = 0.614), and gaps-in-noise (p = 0.230). Dichotic tests in right and left ears respectively: speech in noise (p = 0.949en
dc.description.abstractp = 0.722), dichotic digits test (p = 0.943en
dc.description.abstractp = 0.513). Conclusion: There was no clinical effect with the use of citalopram in central auditory processing tests of the subjects.en
dc.description.affiliationFed Univ Sao Paulo UNIFESP, Dept Otolaryngol & Head & Neck Surg, Sao Paulo, Brazil
dc.description.affiliationFed Univ Parana UFPR, Dept Otorhinolaryngol, Curitiba, Parana, Brazil
dc.description.affiliationUnifespFed Univ Sao Paulo UNIFESP, Dept Otolaryngol & Head & Neck Surg, Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent1233-1239
dc.identifierhttp://dx.doi.org/10.1097/MAO.0000000000001531
dc.identifier.citationOtology & Neurotology. Philadelphia, v. 38, n. 9, p. 1233-1239, 2017.
dc.identifier.doi10.1097/MAO.0000000000001531
dc.identifier.issn1531-7129
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/57184
dc.identifier.wosWOS:000418475600015
dc.language.isoeng
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofOtology & Neurotology
dc.rightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectAgeden
dc.subjectAuditory perceptual disordersen
dc.subjectHearing disordersen
dc.subjectSerotonin uptake inhibitorsen
dc.titleThe Effect of Citalopram Versus a Placebo on Central Auditory Processing in the Elderlyen
dc.typeinfo:eu-repo/semantics/article
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