Wound-healing and benzodiazepines: does sleep play a role in this relationship?

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dc.contributor.authorEgydio, Flavia [UNIFESP]
dc.contributor.authorPires, Gabriel Natan [UNIFESP]
dc.contributor.authorTufik, Sergio [UNIFESP]
dc.contributor.authorAndersen, Monica Levy [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2015-06-14T13:44:49Z
dc.date.available2015-06-14T13:44:49Z
dc.date.issued2012-07-01
dc.description.abstractPatients who have suffered burns frequently experience psychological consequences, among which anxiety disorders are prominent. Benzodiazepines are commonly administered to treat these symptoms. The effects of benzodiazepines on healing may not be direct but rather are modulated by alterations of the sleep architecture. This hypothesis is supported by studies that demonstrate the effects of benzodiazepines on the immune system and the inflammatory profile under both normal sleep conditions and during sleep deprivation, particularly rapid eye movement sleep deprivation.en
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Departamento de Psicobiologia
dc.description.affiliationUnifespUNIFESP, Depto. de Psicobiologia
dc.description.sourceSciELO
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipAssociacao Fundo de Incentivo a Pesquisa (AFIP)
dc.description.sponsorshipFundacao de Amparo a Pesquisa do Estado de Sao Paulo-FAPESP (CEPID)
dc.description.sponsorshipID2011/14462-0 e 2010/14768-0
dc.description.sponsorshipID98/14303-3
dc.format.extent827-830
dc.identifierhttp://dx.doi.org/10.6061/clinics/2012(07)20
dc.identifier.citationClinics. Faculdade de Medicina / USP, v. 67, n. 7, p. 827-830, 2012.
dc.identifier.doi10.6061/clinics/2012(07)20
dc.identifier.fileS1807-59322012000700020.pdf
dc.identifier.issn1807-5932
dc.identifier.scieloS1807-59322012000700020
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/7193
dc.identifier.wosWOS:000307723100020
dc.language.isoeng
dc.publisherFaculdade de Medicina / USP
dc.relation.ispartofClinics
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBenzodiazepinesen
dc.subjectSleep Deprivationen
dc.subjectWound Healingen
dc.subjectBurnsen
dc.subjectImmune Systemen
dc.titleWound-healing and benzodiazepines: does sleep play a role in this relationship?en
dc.typeinfo:eu-repo/semantics/article
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