Reverse Cholesterol Transport: Molecular Mechanisms and the Non-medical Approach to Enhance HDL Cholesterol

dc.contributor.authorMarques, Leandro Ribeiro
dc.contributor.authorDiniz, Tiego Aparecido
dc.contributor.authorAntunes, Barbara Moura
dc.contributor.authorRossi, Fabricio Eduardo
dc.contributor.authorCaperuto, Erico Chagas
dc.contributor.authorLira, Fabio Santos de [UNIFESP]
dc.contributor.authorGonçalves, Daniela Caetano [UNIFESP]
dc.date.accessioned2018-07-26T12:18:47Z
dc.date.available2018-07-26T12:18:47Z
dc.date.issued2018
dc.description.abstractDyslipidemia (high concentrations of LDL-c and low concentrations of HDL-c) is a major cause of cardiovascular events, which are the leading cause of death in the world. On the other hand, nutrition and regular exercise can be an interesting strategy to modulate lipid profile, acting as prevention or treatment, inhibiting the risk of diseases due to its anti-inflammatory and anti-atherogenic characteristics. Additionally, the possibility of controlling different training variables, such as type, intensity and recovery interval, can be used to maximize the benefits of exercise in promoting cardiovascular health. However, the mechanisms by which exercise and nutrients act in the regulation of cholesterol and its fractions, such as reverse cholesterol transport, receptors and transcription factors involved, such as PPARs and their role related to exercise, deserve further discussion. Therefore, the objective of this review is to debate about non-medical approaches to increase HDL-c, such as nutritional and training strategies, and to discuss the central mechanisms involved in the modulation of lipid profile during exercise, as well as that can be controlled by physical trainers or sports specialists in attempt to maximize the benefits promoted by exercise. The search for papers was performed in the databases: Medline (Pubmed), Science Direct, Scopus, Sport Discus, Web of Science, Scielo and Lilacs until February 2016.en
dc.description.affiliationUniv Estadual Paulista, Dept Phys Educ, Exercise & Immunometab Res Grp, Presidente Prudente, Brazil
dc.description.affiliationUniv Sao Paulo, Inst Biomed Sci, Dept Cell & Dev Biol, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Piaui, Dept Phys Educ, Immunometab Skeletal Muscle & Exercise Res Grp, Teresina, Brazil
dc.description.affiliationUniv Sao Judas Tadeu, Human Movement Lab, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Biosci, Santos, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Biosci, Santos, Brazil
dc.description.sourceWeb of Science
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt
dc.description.sponsorshipIDFAPESP: 2016/16712-8pt
dc.description.sponsorshipIDCNPq: 305263/2015-3pt
dc.description.sponsorshipIDCNPq: 444365/2014-1pt
dc.format.extent-
dc.identifierhttps://dx.doi.org/10.3389/fphys.2018.00526
dc.identifier.citationFrontiers In Physiology. Lausanne, v. 9, p. -, 2018.
dc.identifier.doi10.3389/fphys.2018.00526
dc.identifier.fileWOS000432408000001.pdf
dc.identifier.issn1664-042X
dc.identifier.urihttps://repositorio.unifesp.br/handle/11600/46035
dc.identifier.wosWOS:000432408000001
dc.language.isoeng
dc.publisherFrontiers Media Sa
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectExerciseen
dc.subjectPhysical trainingen
dc.subjectFunctional foodsen
dc.subjectNutritional strategiesen
dc.subjectLipoproteinsen
dc.subjectDyslipidemiasen
dc.titleReverse Cholesterol Transport: Molecular Mechanisms and the Non-medical Approach to Enhance HDL Cholesterolen
dc.typeinfo:eu-repo/semantics/review
Arquivos
Pacote Original
Agora exibindo 1 - 1 de 1
Carregando...
Imagem de Miniatura
Nome:
WOS000432408000001.pdf
Tamanho:
793.67 KB
Formato:
Adobe Portable Document Format
Descrição:
Coleções