Impact of Radial and Partial Nephrectomy on Rental Function in Patients with Renal Cancer

Página do item simplificado
dc.contributor.authorKrebs, Rodrigo Ketzer [UNIFESP]
dc.contributor.authorAndreoni, Cássio [UNIFESP]
dc.contributor.authorOrtiz, Valdemar [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2016-01-24T14:35:01Z
dc.date.available2016-01-24T14:35:01Z
dc.date.issued2014-01-01
dc.description.abstractObjective: To evaluate renal function in renal cancer patients undergoing radical nephrectomy (RN) or partial nephrectomy (PN) (open or laparoscopic ORN, OPN, LRN or LPN) and to identify risk factors contributing to renal function loss. Methods: We analysed 228 consecutive renal cancer patients admitted for OPN, LPN, ORN or LRN. the variables analysed were age, gender, weight, type of surgery (radical versus partial), type of surgical access (open versus laparoscopic), preoperative renal function and history of hypertension, diabetes or malignancy. Absolute renal function was calculated as the difference in glomerular filtration rate (AGFR) between the renal function before (GFR(0)) and 12 months after surgery (GFR(12)). the relative renal function of patients undergoing PN and RN was evaluated by the change in chronic kidney disease stage. Results: LRN caused the greatest loss in absolute renal function, followed by ORN, LPN and OPN. A GFR of >= 60 ml/min was noted for 90(68.7%) patients before and 65 (49.6%) patients after RN and for 80 (82.5%) patients before and 74 (76.3%) patients after PN. the chronic kidney disease stage dropped to 4 or 5 in the case preoperative weight and type of surgery (radical versus partial) had a significant impact on renal function. Conclusion: Renal function significantly decreased in patients undergoing RN, irrespective of the access route. Patients With preoperative poor renal function are at risk of postoperative end-stage renal disease. (c) 2014 S. Karger AG, Baselen
dc.description.affiliationUniversidade Federal de São Paulo, Div Urol, BR-04024002 São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Div Urol, BR-04024002 São Paulo, Brazil
dc.description.sourceWeb of Science
dc.format.extent449-454
dc.identifierhttp://dx.doi.org/10.1159/000355609
dc.identifier.citationUrologia Internationalis. Basel: Karger, v. 92, n. 4, p. 449-454, 2014.
dc.identifier.doi10.1159/000355609
dc.identifier.issn0042-1138
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/37207
dc.identifier.wosWOS:000336947700013
dc.language.isoeng
dc.publisherKarger
dc.relation.ispartofUrologia Internationalis
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.licensehttp://www.karger.com/Services/RightsPermissions
dc.subjectRenal canceren
dc.subjectRenal functionen
dc.subjectChronic renal diseaseen
dc.subjectPartial nephrectonnyen
dc.subjectRadical nephrectomyen
dc.titleImpact of Radial and Partial Nephrectomy on Rental Function in Patients with Renal Canceren
dc.typeinfo:eu-repo/semantics/article
Arquivos
Coleções
EPM - Artigos