Laryngeal sequelae of recurrent respiratory papillomatosis surgery in children

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dc.contributor.authorHermann, Juliana Sato [UNIFESP]
dc.contributor.authorPontes, Paulo [UNIFESP]
dc.contributor.authorWeckx, Luc Louis Maurice [UNIFESP]
dc.contributor.authorFujita, Reginaldo Raimundo [UNIFESP]
dc.contributor.authorAvelino, Melissa Ameloti Gomes [UNIFESP]
dc.contributor.authorPignatari, Shirley Shizue Nagata [UNIFESP]
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2015-06-14T13:43:41Z
dc.date.available2015-06-14T13:43:41Z
dc.date.issued2012-04-01
dc.description.abstractOBJECTIVE: To evaluate laryngeal sequelae from surgical treatment of recurrent respiratory papillomatosis in children, as well as associated risk factors. METHODS: Case-control study. Medical record data analysis of 50 children with recurrent respiratory papillomatosis, divided into two groups: with and without laryngeal sequelae. The group of patients with laryngeal sequelae was compared to those without sequelae in regard to the onset of disease, age at first surgery, number and frequency of surgeries, disease stage, and type of surgery (CO2 laser, cold forceps). RESULTS: 23 patients (46%) sustained laryngeal sequelae. The most frequent sequela was anterior commissure synechia (17 patients [34%]), followed by glottic stenosis (six patients [12%]). There was no statistically significant difference between groups with and without laryngeal sequelae regarding the disease onset (p = 0.93), age at first surgery (p = 0.68), number of surgeries (p = 0.22), annual frequency of surgery (p = 0.93), presence of papilloma in anterior (p = 0.430) or posterior commissure (p = 0.39), and type of surgery (p = 0.27). The Derkay anatomical score (a staging system that assesses the extent of the disease in the aerodigestive tract) was significantly higher in the laryngeal sequelae group (p = 0.04). CONCLUSION: Laryngeal sequelae are a frequent complication of recurrent respiratory papillomatosis surgical treatment in children, particularly anterior commissure synechiae and glottic stenosis. Advanced stages are associated with increased risk of laryngeal sequelae after surgery.en
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Department of Otorhinolaryngology and Head and Neck Surgery
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Department of Otorhinolaryngology and Head and Neck Surgery Internal Clinic of the Pediatric Otorhinolaryngology Discipline
dc.description.affiliationUNIFESP
dc.description.affiliationUNIFESP Pediatric Otorhinolaryngology Discipline
dc.description.affiliationUnifespUNIFESP, Department of Otorhinolaryngology and Head and Neck Surgery
dc.description.affiliationUnifespUNIFESP, Department of Otorhinolaryngology and Head and Neck Surgery Internal Clinic of the Pediatric Otorhinolaryngology Discipline
dc.description.affiliationUnifespUNIFESP, Pediatric Otorhinolaryngology Discipline
dc.description.sourceSciELO
dc.format.extent204-208
dc.identifierhttp://dx.doi.org/10.1590/S0104-42302012000200016
dc.identifier.citationHERMANN, Juliana Sato et al . Laryngeal sequelae of recurrent respiratory papillomatosis surgery in children. Rev. Assoc. Med. Bras., São Paulo , v. 58, n. 2, p. 204-208, abr. 2012
dc.identifier.doi10.1590/S0104-42302012000200016
dc.identifier.fileS0104-42302012000200016.pdf
dc.identifier.issn0104-4230
dc.identifier.scieloS0104-42302012000200016
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/7053
dc.identifier.wosWOS:000302926900018
dc.language.isoeng
dc.publisherAssociação Médica Brasileira
dc.relation.ispartofRevista da Associação Médica Brasileira
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPapillomaen
dc.subjectpostoperative complicationsen
dc.subjectdysphoniaen
dc.subjectlaseren
dc.subjecttherapyen
dc.subjectpapillomavirus infectionsen
dc.titleLaryngeal sequelae of recurrent respiratory papillomatosis surgery in childrenen
dc.typeinfo:eu-repo/semantics/article
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